Evidence map›Paper›PMID 39062142›Full record

ArticleBiomedicines2024

Time-Dependent Shifts in Intestinal Bacteriome,

Oleg V Goloshchapov, Alexey B Chukhlovin, Dmitrii E Polev, Yury A Eismont, Dmitry S Bug, Alexey V Kusakin, Oleg V Kosarev, Ruslana V Klementeva, Vladimir V Gostev, Vladimir A Ageevets and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Oleg V GoloshchapovR. Gorbacheva Memorial Research Institute of Pediatric Oncology, Hematology and Transplantation, Pavlov First State Medical University of St. Petersburg, L. Tolstoy St, 6-8, 197022 St. Petersburg, Russia.ORCID 0000-0002-0736-1269
Alexey B ChukhlovinR. Gorbacheva Memorial Research Institute of Pediatric Oncology, Hematology and Transplantation, Pavlov First State Medical University of St. Petersburg, L. Tolstoy St, 6-8, 197022 St. Petersburg, Russia.
Dmitrii E PolevPasteur Institute of Epidemiology and Microbiology, Mira St, 14, 197101 St. Petersburg, Russia.ORCID 0000-0001-9679-2791
Yury A EismontPediatric Research and Clinical Center for Infectious Diseases, Prof. Popov St, 9, 197022 St. Petersburg, Russia.
Dmitry S BugR. Gorbacheva Memorial Research Institute of Pediatric Oncology, Hematology and Transplantation, Pavlov First State Medical University of St. Petersburg, L. Tolstoy St, 6-8, 197022 St. Petersburg, Russia.ORCID 0000-0002-5849-1311
Alexey V KusakinPediatric Research and Clinical Center for Infectious Diseases, Prof. Popov St, 9, 197022 St. Petersburg, Russia.ORCID 0000-0001-9546-7831
Oleg V KosarevDepartment of Informatics and Computer Technologies, St. Petersburg Mining University, 199106 St. Petersburg, Russia.ORCID 0000-0003-3427-6593
Ruslana V KlementevaR. Gorbacheva Memorial Research Institute of Pediatric Oncology, Hematology and Transplantation, Pavlov First State Medical University of St. Petersburg, L. Tolstoy St, 6-8, 197022 St. Petersburg, Russia.
Vladimir V GostevPediatric Research and Clinical Center for Infectious Diseases, Prof. Popov St, 9, 197022 St. Petersburg, Russia.ORCID 0000-0002-3480-8089
Vladimir A AgeevetsPediatric Research and Clinical Center for Infectious Diseases, Prof. Popov St, 9, 197022 St. Petersburg, Russia.ORCID 0000-0002-3963-0144
Nikita P VolkovR. Gorbacheva Memorial Research Institute of Pediatric Oncology, Hematology and Transplantation, Pavlov First State Medical University of St. Petersburg, L. Tolstoy St, 6-8, 197022 St. Petersburg, Russia.ORCID 0000-0001-6161-1444
Anastasia S IpatovaR. Gorbacheva Memorial Research Institute of Pediatric Oncology, Hematology and Transplantation, Pavlov First State Medical University of St. Petersburg, L. Tolstoy St, 6-8, 197022 St. Petersburg, Russia.
Ivan S MoiseevR. Gorbacheva Memorial Research Institute of Pediatric Oncology, Hematology and Transplantation, Pavlov First State Medical University of St. Petersburg, L. Tolstoy St, 6-8, 197022 St. Petersburg, Russia.
Anna A SpiridonovaR. Gorbacheva Memorial Research Institute of Pediatric Oncology, Hematology and Transplantation, Pavlov First State Medical University of St. Petersburg, L. Tolstoy St, 6-8, 197022 St. Petersburg, Russia.
Sergey V SidorenkoPediatric Research and Clinical Center for Infectious Diseases, Prof. Popov St, 9, 197022 St. Petersburg, Russia.ORCID 0000-0003-3550-7875
Alexander D KulaginR. Gorbacheva Memorial Research Institute of Pediatric Oncology, Hematology and Transplantation, Pavlov First State Medical University of St. Petersburg, L. Tolstoy St, 6-8, 197022 St. Petersburg, Russia.ORCID 0000-0002-9589-4136

Funding

Russian Science Foundation 22-15-00149
6 · The paper itself

Abstract

Dose-intensive cytostatic therapy and antibiotic treatment in allogeneic hematopoietic stem cell transplantation (allo-HSCT) cause severe abnormalities in a composition of gut microbiota as well as the emergence of antibiotic resistance. The data on the longitudinal recovery of major bacterial phyla and the expansion of genes associated with antibiotic resistance are limited. We collected regular stool samples during the first year after allo-HSCT from 12 adult patients with oncohematological disorders after allo-HSCT and performed 16SrRNA sequencing, multiplex PCR, conventional bacteriology and CHROMagar testing. We observed a decline in Shannon microbiota diversity index as early as day 0 of allo-HSCT (

Indexed as

allogeneicantibiotic resistance genesBacillotacarbapenem resistantchangesCHROMagar techniqueDNA sequencingEnterobacteriaceaeESBLgut microbiomehematopoietic stem cell transplantationKlebsiella pneumoniae colonizationKPCMDRNDMNGSOXA-48time-dependent

Identifiers

PMID39062142
PMCPMC11274722

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.