ArticleAntioxidants (Basel, Switzerland)2024
Dietary Protease Supplementation Improved Growth Performance and Nutrients Digestion via Modulating Intestine Barrier, Immunological Response, and Microbiota Composition in Weaned Piglets.
Article in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Dietary Supplementation of Protease and/or Amylase Improves Growth Performance, Digestive Function, and Intestinal Health of Weaned Piglets.Animals : an open access journal from MDPI · 2026Article
- Effects of protease-hydrolyzed cottonseed protein on growth performance, intestinal morphology, and bacterial diversity in broilers.Poultry science · 2026Article
- Protease Supplementation Partially Alleviates the Negative Effects of Low-Protein Diets on Growth Performance in Weaned Piglets.Veterinary sciences · 2026Article
- Article
- Glucuronolactone Alleviates Metabolic Stress Induced by High-Fat Diet in Turbot (Antioxidants (Basel, Switzerland) · 2026Article
- Probiotics Modulate the Ruminal Microbiome and Metabolite Availability to Enhance Rumen Barrier Function and Growth Performance in Goats Fed a High-Concentrate Diet.Probiotics and antimicrobial proteins · 2026Article
- Medium and short chain fatty acid monoglycerides as an antibiotic alternative reduce diarrhea, improve growth, and modulate gut microbiota in weaned piglets.Frontiers in veterinary science · 2026Article
- Effects of exogenous protease supplementation of diets containing animal proteins or not on Campylobacter jejuni colonization and on the intestinal microbiota of broiler chickens.Gut pathogens · 2025Article
- The Addition of an Acid Protease Improved the Digestibility of Crude Protein and Amino Acids of Soybean Meal, but Not of Corn, in Piglets.Animals : an open access journal from MDPI · 2025Article
- DietaryVeterinary sciences · 2025Article
- Review
- Zinc oxide nanoparticles improve lactation and metabolism in dairy goats by modulating the rumen microbiota.Frontiers in microbiology · 2024Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Despite mounting evidence for dietary protease benefits, the mechanisms beyond enhanced protein degradation are poorly understood. This study aims to thoroughly investigate the impact of protease addition on the growth performance, intestinal function, and microbial composition of weaned piglets. Ninety 28-day-old weaned pigs were randomly assigned to the following three experimental diets based on their initial body weight for a 28-day experiment: (1) control (CC), a basic diet with composite enzymes without protease; (2) negative control (NC), a diet with no enzymes; and (3) dietary protease (PR), a control diet with protease. The results show that dietary proteases significantly enhanced growth performance and boosted antioxidant capacity, increasing the total antioxidant capacity (T-AOC) levels (
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Registered trials
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