Evidence map›Paper›PMID 39061780›Full record

ArticleBioengineering (Basel, Switzerland)2024

Electrochemical Impedance Spectroscopy in the Determination of the Dielectric Properties of Tau-441 Protein for Dielectrophoresis Response Prediction.

Zuriel Shee Da En, Ervina Efzan Mhd Noor, Aminuddin Ahmed Kayani, Mohd Hazwan Hussin, Mirza Farrukh Baig

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zuriel Shee Da EnCentre for Manufacturing and Environmental Sustainability (CMES), Faculty of Engineering and Technology, Multimedia University, Ayer Keroh 75450, Malaysia.ORCID 0009-0003-1098-7785
Ervina Efzan Mhd NoorCentre for Manufacturing and Environmental Sustainability (CMES), Faculty of Engineering and Technology, Multimedia University, Ayer Keroh 75450, Malaysia.
Aminuddin Ahmed KayaniFunctional Materials and Microsystems Research Group, School of Engineering, RMIT University, Melbourne, VIC 3001, Australia.ORCID 0000-0003-1841-1716
Mohd Hazwan HussinMaterials Technology Research Group (MaTReC), School of Chemical Sciences, Universiti Sains Malaysia, Minden 11800, Malaysia.
Mirza Farrukh BaigCentre for Manufacturing and Environmental Sustainability (CMES), Faculty of Engineering and Technology, Multimedia University, Ayer Keroh 75450, Malaysia.ORCID 0000-0003-1643-368X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study employs electrochemical impedance spectroscopy (EIS) to probe the behavior of Tau-441 protein, a key component implicated in Alzheimer's disease. Through meticulous experimentation and analysis, the impedance of Tau-441 protein suspension revealed a conductivity peak value of 1.02 S/m. The study demonstrates a high level of specificity and selectivity, particularly within the challenging nanomolar concentration range. Additionally, the EIS method enabled the prediction of Tau-441 protein's dielectrophoresis (DEP) response and the determination of the associated frequency range of 1 kHz to 1 MHz. These findings contribute to advancing our understanding of the molecular intricacies surrounding Tau-441 and hold promise for unraveling implications related to Alzheimer's disease. This study establishes a robust foundation for future research on neurodegenerative disease and biosciences, offering valuable insights into the electrochemical dynamics of Tau-441 protein.

Indexed as

Alzheimer’s diseasedielectric propertiesdielectrophoresiselectrochemical impedance spectroscopyTau-441

Identifiers

PMID39061780
PMCPMC11274257

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.