Evidence map›Paper›PMID 39061720›Full record

ArticleBioengineering (Basel, Switzerland)2024

The Fluorescent Cell Line SW620-GFP Is a Valuable Model to Monitor Magnetic Hyperthermia.

Saray Rosales, Rodolfo Hernández-Gutiérrez, Alma Oaxaca, Zaira López, Norberto Casillas, Peter Knauth, Luis H Quintero, José A Paz, Francisco Cholico, Celso Velásquez and 1 more

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Evaluation of CoFeInternational journal of molecular sciences · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Saray RosalesCentro Universitario de Ciencias Exactas e Ingenierías, Universidad de Guadalajara, Marcelino García Barragan 1421, Guadalajara 44430, Jalisco, Mexico.
Rodolfo Hernández-GutiérrezCentro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco A.C., Av. Normalistas 800, Guadalajara 44270, Jalisco, Mexico.ORCID 0000-0001-7566-6825
Alma OaxacaCentro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco A.C., Av. Normalistas 800, Guadalajara 44270, Jalisco, Mexico.
Zaira LópezCentro Universitario de la Ciénega, Universidad de Guadalajara, Avenida Universidad 1115, Ocotlan 47810, Jalisco, Mexico.
Norberto CasillasCentro Universitario de Ciencias Exactas e Ingenierías, Universidad de Guadalajara, Marcelino García Barragan 1421, Guadalajara 44430, Jalisco, Mexico.
Peter KnauthCentro Universitario de la Ciénega, Universidad de Guadalajara, Avenida Universidad 1115, Ocotlan 47810, Jalisco, Mexico.
Luis H QuinteroCentro Universitario de Ciencias Económico Administrativas, Universidad de Guadalajara, Periférico Norte 799, Col. Los Belenes, Zapopan 45100, Jalisco, Mexico.ORCID 0000-0002-9222-927X
José A PazCentro Universitario de la Ciénega, Universidad de Guadalajara, Avenida Universidad 1115, Ocotlan 47810, Jalisco, Mexico.
Francisco CholicoCentro Universitario de la Ciénega, Universidad de Guadalajara, Avenida Universidad 1115, Ocotlan 47810, Jalisco, Mexico.
Celso VelásquezCentro Universitario de los Valles, Universidad de Guadalajara, Carretera Guadalajara-Ameca Km. 45.5, Ameca 46600, Jalisco, Mexico.
Mario E CanoCentro Universitario de la Ciénega, Universidad de Guadalajara, Avenida Universidad 1115, Ocotlan 47810, Jalisco, Mexico.

Funding

Consejo Nacional de Humanidades, Ciencias y Tecnologías 568483/2020
6 · The paper itself

Abstract

In this work, the cell line SW620-GFP has been used in a complete magnetic hyperthermia assay, from the preparation of the ferrofluid with folate-coated iron oxide nanoparticles to in vivo experiments. The physical and chemical characterization of the nanoparticles evidenced their superparamagnetic behaviour, an average diameter of 12 ± 4 nm, a 2 nm coat thickness, and a high-power loss density. The main innovation of the work is the exclusive capability of viable SW620-GFP cells to emit fluorescence, enabling fast analysis of both, cell viability in vitro with an epifluorescence microscope and tumour size and shape in vivo in a non-invasive manner using the iBox technology. Moreover, with this imaging technique, it was possible to demonstrate the successful tumour size reduction in mice applying magnetic hyperthermia three times a week over 3 weeks.

Indexed as

fluorescencehyperthermiananoparticles

Identifiers

PMID39061720
PMCPMC11274270

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.