ReviewDiagnostics (Basel, Switzerland)2024
Adverse Effects Associated with Dermal Filler Treatments: Part II Vascular Complication.
Review in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Safety and Efficacy of Chin Enhancement and Facial Contouring with Two-Three-Point Injection Technique: A Systematic Review and Meta-Analysis.Aesthetic plastic surgery · 2026Pooled it
- Guide for Managing Vascular Occlusion Caused by Fillers with Exclusive Cutaneous Involvement: A Review of Diagnosis, Classification, and Treatment.Aesthetic plastic surgery · 2026Pooled it
- Adverse Events in Nonsurgical Facial Aesthetic Procedures: A Systematic Review and Meta-Analysis.Oral diseases · 2026Pooled it
- Filler Injection Between the Superficial and Deep Temporal Fascia and Diameter of Superficial Temporal Arteries for Temple Augmentation: A Systematic Review and Meta-Analysis.Journal of cosmetic dermatology · 2026Pooled it
- Investigation of Vascular Behaviour and Tissue Response Following Intra-Arterial Injection of Poly D,L-Lactic Acid with Hyaluronic Acid Hybrid Biostimulators (JuvelookJournal of functional biomaterials · 2026Article
- Comparative Content Analysis and Expert Physician Risk Assessment of Aesthetic Procedures Promoted on TikTok in Taiwan: Quantitative Study.JMIR infodemiology · 2026Article
- Safety Profile in Hyaluronic Acid-Based Vocal Fold Injection Augmentation.The Laryngoscope · 2026Article
- Hyaluronic Acid Fillers Versus Polynucleotides for Under-Eye Rejuvenation.Journal of clinical medicine · 2026Review
- Ultrasound imaging in aesthetic medicine: safety and precision in injectable procedures.Journal of ultrasound · 2026Review
- Article
- Cannula is safer than needle in filler injection?JPRAS open · 2026Review
- Management of Ischemia and Necrosis Following Nonsurgical Rhinoplasty With Hyaluronic Acid: A Case Report.Cureus · 2026Article
- The Usefulness of High-Frequency Ultrasound in Assessing Complications After Minimally Invasive Aesthetic Medicine Procedures, Using the Example of Assessing Blood Flow in the Dorsal Artery of the Nose.Diagnostics (Basel, Switzerland) · 2026Article
- Staged Management of Vascular Occlusion With Ellansé (Polycaprolactone): A Modified Delphi Expert Consensus.Aesthetic surgery journal. Open forum · 2026Article
- Facial Overfilled Syndrome: A Narrative Clinical Review.Clinical, cosmetic and investigational dermatology · 2026Review
- Hyaluronidase Use in Aesthetic Medicine: Formulations, Safety, and Clinical Practice.Journal of clinical medicine · 2025Review
- Tear Trough Rejuvenation With Injectable Biostimulatory Polynucleotides (VAMP).Plastic and reconstructive surgery. Global open · 2025Article
- Application of High-frequency Ultrasound for Detection and Characterization of Dermal Fillers in the Periorbital Region.Plastic and reconstructive surgery. Global open · 2025Article
- Vascular Embolism After Dull Needle Injection of Hyaluronic Acid Into Glabellar Wrinkles in Preformed Subdermal Tunnels: A Case Report and Review of the Literature.Journal of cosmetic dermatology · 2025Review
- The SIBUS-IN Fingerheld Ultrasound Machine.Journal of cosmetic dermatology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vascular complications arising from dermal filler treatments pose significant risks, including ischemia, tissue necrosis, and severe outcomes like blindness and pulmonary embolism. This study investigates the mechanisms of vascular complications, categorizing them into extravascular compression and intravascular emboli. Extravascular compression occurs when injected fillers compress adjacent blood vessels, leading to ischemia and potential necrosis, while intravascular emboli result from fillers entering blood vessels, causing blockages. The study emphasizes the importance of anatomical knowledge, careful injection techniques, and early intervention. Management strategies include the use of hyaluronidase to dissolve HA fillers, vasodilators to improve blood circulation, and hyperbaric oxygen therapy. The regions most susceptible to complications align with major arterial pathways, particularly the nasolabial folds and nasal region. The study also highlights the need for meticulous injection techniques, the use of cannulas over needles in high-risk areas, and the aspiration test to detect vessel penetration. Early detection and immediate intervention are crucial to mitigate adverse outcomes. Continuous education and training for practitioners, along with advancements in filler materials and injection methods, are essential for improving the safety of cosmetic procedures. This comprehensive understanding aids in preventing and managing vascular complications, ensuring better patient outcomes. The field of dermal filler treatments is advancing with new techniques and technologies, such as High-Resolution Ultrasound, Infrared Imaging, self-crossing hyaluronic acid filler, biodegradable microspheres, and microinjection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.