Evidence map›Paper›PMID 39061599›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Neonatal Outcomes after Maternal Biomarker-Guided Preterm Birth Intervention: The AVERT PRETERM Trial.

Matthew K Hoffman, Carrie Kitto, Zugui Zhang, Jing Shi, Michael G Walker, Babak Shahbaba, Kelly Ruhstaller

Registry-linked trialAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03151330 (Serum Assessment of Preterm Birth), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03151330 nacompletednot on this map

Serum Assessment of Preterm Birth: Outcomes Compared to Historical Controls

TypeinterventionalSponsorChristiana Care Health ServicesRan2018 to 2024Enrolled1,873ConditionsPreterm BirthArmsScreened Arm
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Matthew K HoffmanDepartment of Obstetrics and Gynecology, ChristianaCare, Newark, DE 19718, USA.ORCID 0000-0002-2927-8693
Carrie KittoDepartment of Obstetrics and Gynecology, ChristianaCare, Newark, DE 19718, USA.
Zugui ZhangDepartment of Obstetrics and Gynecology, ChristianaCare, Newark, DE 19718, USA.
Jing ShiWalker Bioscience, Carlsbad, CA 92009, USA.
Michael G WalkerWalker Bioscience, Carlsbad, CA 92009, USA.ORCID 0009-0004-2677-794X
Babak ShahbabaDepartments of Statistics and Computer Science, University of California Irvine, Irvine, CA 92697, USA.
Kelly RuhstallerDepartment of Obstetrics and Gynecology, ChristianaCare, Newark, DE 19718, USA.

Funding

Sera Prognostics, Inc. NA
6 · The paper itself

Abstract

The AVERT PRETERM trial (NCT03151330) evaluated whether screening clinically low-risk pregnancies with a validated maternal blood biomarker test for spontaneous preterm birth (sPTB) risk, followed by preventive treatments for those screening positive, would improve neonatal outcomes compared to a clinically low-risk historical population that had received the usual care. Prospective arm participants with singleton non-anomalous pregnancies and no PTB history were tested for sPTB risk at 19

Indexed as

biomarker test-and-treat strategyneonatal outcomespreterm birthPreTRMprotein biomarker risk predictorspontaneous preterm birth

Identifiers

PMID39061599
PMCPMC11275486

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.