Evidence map›Paper›PMID 39061366›Full record

ReviewBrain sciences2024

Imbalance and Falls in Patients with Parkinson's Disease: Causes and Recent Developments in Training and Sensor-Based Assessment.

Veit Mylius, Elisabeth Zenev, Caroline S Brook, Florian Brugger, Walter Maetzler, Roman Gonzenbach, Anisoara Paraschiv-Ionescu

Abstract readReview
In one paragraph

Review in Brain sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Parkinson's disease severity and treatment classification in interpreting bisphosphonate-associated fracture risk.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Veit MyliusDepartment of Neurology, Center for Neurorehabilitation, 7317 Valens, Switzerland.ORCID 0000-0002-0900-0491
Elisabeth ZenevDepartment of Neurology, Center for Neurorehabilitation, 7317 Valens, Switzerland.ORCID 0009-0003-2914-2520
Caroline S BrookDepartment of Neurology, Center for Neurorehabilitation, 7317 Valens, Switzerland.
Florian BruggerDepartment of Neurology, Kantonsspital St. Gallen, 9007 St. Gallen, Switzerland.
Walter MaetzlerDepartment of Neurology, University Hospital Schleswig-Holstein, Kiel University, 24105 Kiel, Germany.ORCID 0000-0002-5945-4694
Roman GonzenbachDepartment of Neurology, Center for Neurorehabilitation, 7317 Valens, Switzerland.
Anisoara Paraschiv-IonescuSignal Processing Laboratory 5, Ecole Polytechnique Federale de Lausanne (EPFL), 1015 Lausanne, Switzerland.ORCID 0000-0002-2341-4383

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Imbalance and falls in patients with Parkinson's disease (PD) do not only reduce their quality of life but also their life expectancy. Aging-related symptoms as well as disease-specific motor and non-motor symptoms contribute to these conditions and should be treated when appropriate. In addition to an active lifestyle, advanced exercise training is useful and effective, especially for less medically responsive symptoms such as freezing of gait and postural instability at advanced stages. As treadmill training in non-immersive virtual reality, including dual tasks, significantly reduced the number of falls in PD patients, the mechanism(s) explaining this effect should be further investigated. Such research could help to select the most suitable patients and develop the most effective training protocols based on this novel technology. Real-life digital surrogate markers of mobility, such as those describing aspects of endurance, performance, and the complexity of specific movements, can further improve the quality of mobility assessment using wearables.

Indexed as

clinical researchfallsimbalanceParkinson’s diseasetechnology

Identifiers

PMID39061366
PMCPMC11274436

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.