Evidence map›Paper›PMID 39061330›Full record

ReviewAntibiotics (Basel, Switzerland)2024

New Agents Are Coming, and So Is the Resistance.

J Myles Keck, Alina Viteri, Jacob Schultz, Rebecca Fong, Charles Whitman, Madeline Poush, Marlee Martin

Abstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

J Myles KeckDepartment of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.ORCID 0009-0005-1327-8313
Alina ViteriDepartment of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.ORCID 0009-0002-9287-0726
Jacob SchultzIndependent Researcher, Thonotosassa, FL 33592, USA.
Rebecca FongDepartment of Pharmacy, Central Arkansas Veterans Healthcare System, Little Rock, AR 72205, USA.
Charles WhitmanDepartment of Pharmacy, Central Arkansas Veterans Healthcare System, Little Rock, AR 72205, USA.
Madeline PoushDepartment of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Marlee MartinDepartment of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance is a global threat that requires urgent attention to slow the spread of resistant pathogens. The United States Centers for Disease Control and Prevention (CDC) has emphasized clinician-driven antimicrobial stewardship approaches including the reporting and proper documentation of antimicrobial usage and resistance. Additional efforts have targeted the development of new antimicrobial agents, but narrow profit margins have hindered manufacturers from investing in novel antimicrobials for clinical use and therefore the production of new antibiotics has decreased. In order to combat this, both antimicrobial drug discovery processes and healthcare reimbursement programs must be improved. Without action, this poses a high probability to culminate in a deadly post-antibiotic era. This review will highlight some of the global health challenges faced both today and in the future. Furthermore, the new Infectious Diseases Society of America (IDSA) guidelines for resistant Gram-negative pathogens will be discussed. This includes new antimicrobial agents which have gained or are likely to gain FDA approval. Emphasis will be placed on which human pathogens each of these agents cover, as well as how these new agents could be utilized in clinical practice.

Indexed as

antibioticsantimicrobial resistanceantimicrobial stewardshipglobal healthinfectious diseasesmulti-drug resistance

Identifiers

PMID39061330
PMCPMC11273847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.