Evidence map›Paper›PMID 39061255›Full record

ArticleAntibiotics (Basel, Switzerland)2024

Phylogenetic Analysis of the Genes in D-Ala-D-Lactate Synthesizing Glycopeptide Resistance Operons: The Different Origins of Functional and Regulatory Genes.

Gábor Kardos, Levente Laczkó, Eszter Kaszab, Bálint Timmer, Krisztina Szarka, Eszter Prépost, Krisztián Bányai

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Frontiers in immunology · 2025
    Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gábor KardosInstitute of Metagenomics, University of Debrecen, H-4032 Debrecen, Hungary.
Levente LaczkóOne Health Institute, Faculty of Health Sciences, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0002-9379-7527
Eszter KaszabOne Health Institute, Faculty of Health Sciences, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0002-5750-1872
Bálint TimmerInstitute of Metagenomics, University of Debrecen, H-4032 Debrecen, Hungary.
Krisztina SzarkaInstitute of Metagenomics, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0002-7032-9659
Eszter PrépostDepartment of Health Industry, University of Debrecen, H-4032 Debrecen, Hungary.
Krisztián BányaiPathogen Discovery Group, HUN-REN Veterinary Medical Research Institute, H-1143 Budapest, Hungary.

Funding

Eötvös Loránd Research Network SA-27/2021GINOP GINOP-2.3.4-15-2020-00008National Research, Development and Innovation Office RRF-2.3.1-21-2022-00001National Research, Development and Innovation Office TKP2021-EGA-01New National Excellence Program of the Ministry for Innovation and Technology ÚNKP-20-4-I-DE-277
6 · The paper itself

Abstract

The phylogenetic relationships of glycopeptide resistance proteins were investigated. The amino acid sequences of vanA, vanB, vanR and vanS were used as queries to search against bacterial genomes in the NCBI RefSeq database. Hits with >60% amino acid identity and >90% query coverage were aligned, and phylogenetic trees were reconstructed. The ligase gene phylogenies were highly similar for both queries, revealing two major clusters. One contained [[vanA:vanM][vanB:vanD]vanF] and related proteins, with proteins from different Bacillaceae, mostly from

Indexed as

antimicrobial resistancePaenibacillusphylogenyStreptomyces

Identifiers

PMID39061255
PMCPMC11273654

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.