Evidence map›Paper›PMID 39061169›Full record

ArticleCancers2024

miRNA Expression Profiling in G1 and G2 Pancreatic Neuroendocrine Tumors.

Gábor Nyirő, Bálint Kende Szeredás, Ábel Decmann, Zoltan Herold, Bálint Vékony, Katalin Borka, Katalin Dezső, Attila Zalatnai, Ilona Kovalszky, Peter Igaz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gábor NyirőDepartment of Endocrinology, Faculty of Medicine, Semmelweis University, Korányi Str. 2/a, 1083 Budapest, Hungary.ORCID 0000-0002-0248-0007
Bálint Kende SzeredásDepartment of Endocrinology, Faculty of Medicine, Semmelweis University, Korányi Str. 2/a, 1083 Budapest, Hungary.ORCID 0009-0005-4154-1107
Ábel DecmannDr. László Vass Health Center, Municipality of District XV, 1152 Budapest, Hungary.ORCID 0000-0002-4635-8644
Zoltan HeroldDivision of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, Baross Str. 23-25, 1082 Budapest, Hungary.ORCID 0000-0001-5990-4889
Bálint VékonyDepartment of Endocrinology, Faculty of Medicine, Semmelweis University, Korányi Str. 2/a, 1083 Budapest, Hungary.ORCID 0000-0002-6814-7311
Katalin BorkaDepartment of Pathology, Forensic and Insurance Medicine, Faculty of Medicine, Semmelweis University, Üllői Str. 93, 1083 Budapest, Hungary.
Katalin DezsőDepartment of Pathology and Experimental Cancer Research, Faculty of Medicine, Semmelweis University, Üllői Str. 26, 1085 Budapest, Hungary.
Attila ZalatnaiDepartment of Pathology and Experimental Cancer Research, Faculty of Medicine, Semmelweis University, Üllői Str. 26, 1085 Budapest, Hungary.
Ilona KovalszkyDepartment of Pathology and Experimental Cancer Research, Faculty of Medicine, Semmelweis University, Üllői Str. 26, 1085 Budapest, Hungary.ORCID 0000-0002-0179-3378
Peter IgazDepartment of Endocrinology, Faculty of Medicine, Semmelweis University, Korányi Str. 2/a, 1083 Budapest, Hungary.ORCID 0000-0003-2192-554X

Funding

National Academy of Scientist Education Program of the National Biomedical FoundationNational Research, Development and Innovation Fund, Hungary TKP2021-EGA-24National Research, Development and Innovation Office K134215National Research, Development and Innovation Office K146906
6 · The paper itself

Abstract

Pancreatic neuroendocrine neoplasms pose a growing clinical challenge due to their rising incidence and variable prognosis. The current study aims to investigate microRNAs (miRNA; miR) as potential biomarkers for distinguishing between grade 1 (G1) and grade 2 (G2) pancreatic neuroendocrine tumors (PanNET). A total of 33 formalin-fixed, paraffin-embedded samples were analyzed, comprising 17 G1 and 16 G2 tumors. Initially, literature-based miRNAs were validated via real-time quantitative reverse transcription polymerase chain reaction (RT-qPCR), confirming significant downregulation of

Indexed as

biomarkerformalin-fixed paraffin-embeddedgrademachine learningmicroRNApancreatic neuroendocrine tumor

Identifiers

PMID39061169
PMCPMC11275009

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.