ArticleAnnals of nuclear medicine2024
Tubarial salivary glands show a low relative contribution to functional salivary gland tissue mass.
Article in Annals of nuclear medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Tubarial glands as sentinels for environmental toxin-induced salivary dysplasia in endemic nasopharyngeal carcinoma regions.Annals of medicine and surgery (2012) · 2025Article
- Tubarial salivary gland in dentistry: A review.Bioinformation · 2025Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn 2021, the tubarial salivary glands (TSGs) were newly identified on prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) as macroscopic glands in the nasopharyngeal wall. However, the relative contribution of the TSGs to the total salivary gland function, and consequently on the development of xerostomia after external beam radiotherapy (EBRT) or PSMA-targeted radionuclide therapy (RNT) is not known. Therefore, we aimed to determine the presence of the TSGs and to quantify uptake in the TSGs on PSMA PET.
methodsQualitative and quantitative analyses were performed on
resultsThe TSGs were visible on 95% of the
conclusionsThe SUVmean, SUVmax and TO-PSMA of the TSGs were most comparable to the SLSGs. However, the measured PSMA uptake may be disproportional towards the saliva production. Therefore, future studies should focus on the relation between PSMA uptake and salivary function before and after PSMA therapy.
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