Evidence map›Paper›PMID 39060732›Full record

ReviewAdvances in experimental medicine and biology2024

Targeting Food Allergy with Probiotics.

Laura Carucci, Serena Coppola, Rosilenia Carandente, Roberto Berni Canani

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in experimental medicine and biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laura CarucciDepartment of Translational Medical Science at the University of Naples Federico II, Naples, Italy.
Serena CoppolaDepartment of Translational Medical Science at the University of Naples Federico II, Naples, Italy.
Rosilenia CarandenteDepartment of Translational Medical Science at the University of Naples Federico II, Naples, Italy.
Roberto Berni CananiDepartment of Translational Medical Science at the University of Naples Federico II, Naples, Italy. berni@unina.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The globally dramatic increase in food allergy prevalence and severity is demanding effective preventive and therapeutic strategies. Food allergy derives from a defect of immune tolerance mechanisms. Immune tolerance is modulated by gut microbiome composition and function, and gut microbiome dysbiosis has been associated with the development of food allergy. Selected probiotic strains could regulate immune tolerance mechanisms. The mechanisms are multiple and are still not completely defined. Increasing evidence is providing useful information on the choice of optimal bacterial species/strains, dosage, and timing for intervention. The increased knowledge on the crucial role played by postbiotic gut microbiome-derived metabolites, such as butyrate, is also opening the way to a post- biotic approach in the stimulation of immune tolerance.

Indexed as

DysbiosisFood HypersensitivityGastrointestinal MicrobiomeImmune ToleranceProbioticsAnimalsHumansButyrateCow’s milk allergyGut microbiomeImmune TolerancePostbiotics

Identifiers

PMID39060732

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.