Evidence map›Paper›PMID 39060717›Full record

ArticleJournal of ultrasound2024

Exploring diaphragmatic response to high-flow nasal cannula in patients with COVID-19 pneumonia using ultrasound: a proof of concept study.

Issac Cheong, Federico Matías Álvarez Vilariño, José Patricio Gaggino, Raúl Alejandro Gómez, Francisco Marcelo Tamagnone

Abstract read
In one paragraph

Article in Journal of ultrasound, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Issac CheongDepartment of Critical Care Medicine, Sanatorio De los Arcos, Juan B. Justo 909, Buenos Aires, Argentina. issac_cheong@hotmail.com.ORCID http://orcid.org/0000-0002-8231-1528
Federico Matías Álvarez VilariñoDepartment of Critical Care Medicine, Sanatorio De los Arcos, Juan B. Justo 909, Buenos Aires, Argentina.
José Patricio GagginoDepartment of Critical Care Medicine, Sanatorio De los Arcos, Juan B. Justo 909, Buenos Aires, Argentina.
Raúl Alejandro GómezDepartment of Critical Care Medicine, Sanatorio De los Arcos, Juan B. Justo 909, Buenos Aires, Argentina.
Francisco Marcelo TamagnoneArgentinian Critical Care Ultrasonography Association (ASARUC), Buenos Aires, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent studies have highlighted the recognition of diaphragmatic dysfunction as a significant factor contributing to respiratory disturbances in severely ill COVID-19 patients. In the field of noninvasive respiratory support, high-flow nasal cannula (HFNC) has shown effectiveness in relieving diaphragm dysfunction. This study aims to investigate the diaphragmatic response to HFNC in patients with COVID-19 pneumonia by utilizing ultrasound.

methodsThis retrospective study was conducted in a medical-surgical intensive care unit (ICU) at a tertiary care center in Buenos Aires, Argentina (Sanatorio de Los Arcos) over a 16-month period (January 2021-June 2022). The study included patients admitted to the ICU with a diagnosis of COVID-19 pneumonia who were deemed suitable candidates for HFNC therapy by the attending physician. Diaphragm ultrasound was conducted, measuring diaphragmatic excursion (DE) both before and during the utilization of HFNC for these patients.

resultsA total of 10 patients were included in the study. A statistically significant decrease in respiratory rate was observed with the use of HFNC (p = 0.02), accompanied by a significant increase in DE (p = 0.04).

conclusionHFNC leads to a reduction in respiratory rate and an increase in DE as observed by ultrasound in patients with COVID-19 pneumonia, indicating promising enhancements in respiratory mechanics. However, further research is required to validate these findings.

Indexed as

CannulaCOVID-19DiaphragmUltrasonographyAdultAgedFemaleHumansIntensive Care UnitsMaleMiddle AgedNoninvasive VentilationOxygen Inhalation TherapyProof of Concept StudyRespiratory RateRetrospective StudiesCOVID-19DiaphragmDiaphragmatic dysfunctionDiaphragmatic excursionSonographyUltrasound

Identifiers

PMID39060717
PMCPMC11333638

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.