Evidence map›Paper›PMID 39060524›Full record

ReviewAmino acids2024

Targeting the sulfur-containing amino acid pathway in leukemia.

Xiaoyan Chen, Jiahui Jin, Rui Chang, Xing Yang, Na Li, Xi Zhu, Linlin Ma, Yanfei Li

Abstract readReview
In one paragraph

Review in Amino acids, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Enhanced peroxidase-like activity of L-glutamic acid-coated FeAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
    Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaoyan Chen *The College of Medical Technology, Shanghai University of Medicine and Health Sciences, Shanghai, 201318, China.
Jiahui Jin *The College of Medical Technology, Shanghai University of Medicine and Health Sciences, Shanghai, 201318, China.
Rui ChangThe College of Medical Technology, Shanghai University of Medicine and Health Sciences, Shanghai, 201318, China.
Xing YangThe College of Medical Technology, Shanghai University of Medicine and Health Sciences, Shanghai, 201318, China.
Na LiThe College of Medical Technology, Shanghai University of Medicine and Health Sciences, Shanghai, 201318, China.
Xi ZhuShanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, 1500 Zhouyuan Road, Pudong new area, Shanghai, 201318, China.
Linlin MaThe College of Medical Technology, Shanghai University of Medicine and Health Sciences, Shanghai, 201318, China.
Yanfei LiShanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, 1500 Zhouyuan Road, Pudong new area, Shanghai, 201318, China. liyf@sumhs.edu.cn.

Funding

Biomedical Technology Support Special Project of "Shanghai Science and Technology Innovation Action Plan" 21S11901700Pudong New District Academic Leaders Programme PWRd2021-17Shanghai Natural Science Foundation 21ZR1428400Shanghai Pujiang Program 2021PJD027
6 · The paper itself

Abstract

sulfur-containing amino acids have been reported to patriciate in gene regulation, DNA methylation, protein synthesis and other physiological or pathological processes. In recent years, metabolism-related molecules of sulfur-containing amino acids affecting the occurrence, development and treatment of tumors have been implicated in various disorders, especially in leukemia. Here, we summarize current knowledge on the sulfur-containing amino acid metabolism pathway in leukemia and examine ongoing efforts to target this pathway, including treatment strategies targeting (a) sulfur-containing amino acids, (b) metabolites of sulfur-containing amino acids, and (c) enzymes and cofactors related to sulfur-containing amino acid metabolism in leukemia. Future leukemia therapy will likely involve innovative strategies targeting the sulfur-containing amino acid metabolism pathway.

Indexed as

LeukemiaAmino AcidsAmino Acids, SulfurAnimalsAntineoplastic AgentsHumansSulfurAmino AcidsAmino Acids, SulfurAntineoplastic AgentsSulfurLeukemiaMetabolitesMethylationSulfur-containing amino acidsTrans-sulfuration

Identifiers

PMID39060524
PMCPMC11281984

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.