Evidence map›Paper›PMID 39060175›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Calmodulin Triggers Activity-Dependent rRNA Biogenesis via Interaction with DDX21.

Jia-Lin Yang, Xue Sun, Jun-Xiu Shi, Qing-Xu Cui, Xin-Yu Cao, Kai-Tuo Wang, Ming-Xin An, Si-Jin Wu, Yong-Liang Yang, Hong-Zan Sun and 1 more

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Gene expression regulation by CaCellular & molecular biology letters · 2026
    Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jia-Lin YangDepartment of Developmental Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, China Medical University, Shenyang 110122, China.ORCID 0000-0001-9189-4385
Xue SunDepartment of Developmental Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, China Medical University, Shenyang 110122, China.
Jun-Xiu ShiDepartment of Developmental Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, China Medical University, Shenyang 110122, China.
Qing-Xu CuiDepartment of Developmental Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, China Medical University, Shenyang 110122, China.
Xin-Yu CaoDepartment of Developmental Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, China Medical University, Shenyang 110122, China.
Kai-Tuo WangDepartment of Developmental Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, China Medical University, Shenyang 110122, China.
Ming-Xin AnDepartment of Developmental Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, China Medical University, Shenyang 110122, China.
Si-Jin WuAcademy of Pharmacy, Xi'an Jiaotong-Liverpool University, Suzhou 215123, China.
Yong-Liang YangSchool of Bioengineering, Dalian University of Technology, Dalian 116024, China wdzhao@cmu.edu.cn sunhongzan@126.com everbright99@foxmail.com.
Hong-Zan SunDepartment of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, China wdzhao@cmu.edu.cn sunhongzan@126.com everbright99@foxmail.com.
Wei-Dong ZhaoDepartment of Developmental Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, China Medical University, Shenyang 110122, China wdzhao@cmu.edu.cn sunhongzan@126.com everbright99@foxmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein synthesis in response to neuronal activity, known as activity-dependent translation, is critical for synaptic plasticity and memory formation. However, the signaling cascades that couple neuronal activity to the translational events remain elusive. In this study, we identified the role of calmodulin (CaM), a conserved Ca

Indexed as

CalmodulinDEAD-box RNA HelicasesHippocampusRNA, RibosomalAnimalsCalciumCell NucleolusCells, CulturedHEK293 CellsHumansMiceNeuronsRatsCalciumCalmodulinDDX21 protein, humanDEAD-box RNA HelicasesRNA, Ribosomalactivity-dependent translationCa2+calmodulinDDX21rRNA synthesis

Identifiers

PMID39060175
PMCPMC11358605

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.