ArticleAmerican journal of epidemiology2025
Associations of social engagement and loneliness with the progression and reversal of frailty: longitudinal investigations of 2 prospective cohorts from the UK and the USA.
Article in American journal of epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Oral functional limitation and risk of frailty onset in older adults: a sex-stratified 4-Year cohort study with competing risk analysis.GeroScience · 2026Article
- The dynamic association between loneliness and social participation among Chinese middle-aged and older adults.BMC psychology · 2026Article
- Development of a frailty screening tool using components from clinical parameters and frailty criteria for Thai community-dwelling older adults.BMC geriatrics · 2026Observational
- Longitudinal transitions in frailty and health-related quality of life investigated by a 5-year community study.Scientific reports · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Social connections may impact the dynamic trajectory of frailty. Using data from the British Regional Heart Study (BRHS) in the UK (n = 715) and the US Health, Aging and Body Composition (Health ABC) Study (n = 1256), we conducted multinominal regression analyses to examine the association of baseline and change in social engagement and loneliness with progression to prefrailty and frailty, as well as their association with reversal to prefrailty and robust status among older adults. A higher level of social engagement at baseline (BRHS: relative risk ratio [RRR] 0.69 [95% CI, 0.55-0.85]; Health ABC: 0.56 [0.45-0.70]) and an increase in social engagement (BRHS: 0.73 [0.59-0.90]; Health ABC: 0.51 [0.41-0.63]) were associated with a lower risk of developing frailty. In BRHS, a higher level of loneliness at baseline (1.42 [1.10-1.83]) and an increase in loneliness (1.50 [1.18-1.90]) raised the risk of developing frailty. For reversal of frailty, higher social engagement at baseline (Health ABC: 1.63 [1.08-2.47]) and an increase in social engagement (BRHS: 1.74 [1.18-2.50]; Health ABC: 1.79 [1.17-.274]) were beneficial. Social connections may be potentially important and modifiable factors in both preventing and reversing progression of frailty in older adults.
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