Evidence map›Paper›PMID 39060168›Full record

ArticleRNA (New York, N.Y.)2024

Boosting the toolbox for live imaging of translation.

Maëlle Bellec, Ruoyu Chen, Jana Dhayni, Antonello Trullo, Damien Avinens, Hussein Karaki, Flavia Mazzarda, Helene Lenden-Hasse, Cyril Favard, Ruth Lehmann and 3 more

Abstract read
In one paragraph

Article in RNA (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Translation Dynamics of Single mRNAs in Live Cells.Annual review of biophysics · 2024
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Maëlle BellecInstitut de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, 34293 Montpellier, France.
Ruoyu ChenVilcek Institute of Graduate Studies, NYU School of Medicine, New York 10016, USA.
Jana DhayniInstitut de Génétique Humaine, University of Montpellier, CNRS, 34396 Montpellier, France.
Antonello TrulloInstitut de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, 34293 Montpellier, France.
Damien AvinensInstitut de Recherche en Infectiologie de Montpellier, CNRS UMR 9004, University of Montpellier, Montpellier, 34293 Cedex 5, France.
Hussein KarakiInstitut de Génétique Humaine, University of Montpellier, CNRS, 34396 Montpellier, France.
Flavia MazzardaInstitut de Génétique Humaine, University of Montpellier, CNRS, 34396 Montpellier, France.
Helene Lenden-HasseInstitut de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, 34293 Montpellier, France.
Cyril FavardInstitut de Recherche en Infectiologie de Montpellier, CNRS UMR 9004, University of Montpellier, Montpellier, 34293 Cedex 5, France.
Ruth LehmannWhitehead Institute for Biomedical Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.ORCID 0000-0002-8454-5651
Edouard BertrandInstitut de Génétique Humaine, University of Montpellier, CNRS, 34396 Montpellier, France jeremy.dufourt@irim.cnrs.fr edouard.bertrand@igh.cnrs.fr.
Mounia LaghaInstitut de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, 34293 Montpellier, France.ORCID 0000-0002-7082-1950
Jeremy DufourtInstitut de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, 34293 Montpellier, France jeremy.dufourt@irim.cnrs.fr edouard.bertrand@igh.cnrs.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Live imaging of translation based on tag recognition by a single-chain antibody is a powerful technique to assess translation regulation in living cells. However, this approach is challenging and requires optimization in terms of expression level and detection sensitivity of the system, especially in a multicellular organism. Here, we improved existing fluorescent tools and developed new ones to image and quantify nascent translation in the living

Indexed as

Green Fluorescent ProteinsProtein BiosynthesisAnimalsDrosophilaDrosophila melanogasterHumansMolecular ImagingRNA, MessengerSingle-Chain AntibodiesSingle-Domain AntibodiesGreen Fluorescent ProteinsRNA, MessengerSingle-Chain AntibodiesSingle-Domain AntibodiesDrosophilalive-imagingmicroscopytranslation

Identifiers

PMID39060168
PMCPMC11404453

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.