Evidence map›Paper›PMID 39058984›Full record

ArticleRhode Island medical journal (2013)2024

Structure and Function Are Not the Same: The Case for Restoring Mechanoreceptor Continuity Following Anterior Cruciate Ligament Injury.

Jillian E Beveridge, Payam Zandiyeh, Brett D Owens, Ata M Kiapour, Braden C Fleming

Abstract read
In one paragraph

Article in Rhode Island medical journal (2013), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jillian E BeveridgeAssistant Professor in the Department of Orthopaedics, Rhode Island Hospital/ Warren Alpert Medical School of Brown University in Providence, RI.
Payam ZandiyehAssistant Professor in the Department of Orthopaedic Surgery at McGovern Medical School at University of Texas Health Science Center in Houston, TX.
Brett D OwensProfessor of Orthopaedic Surgery at the Warren Alpert Medical School of Brown University and Chief of Sports Medicine at Miriam Hospital in Providence, RI.
Ata M KiapourAssistant Professor in the Department of Orthopaedic Surgery and Sports Medicine at Boston Children's Hospital, Harvard Medical School in Boston, MA.
Braden C FlemingLucy Lippitt Professor of Orthopaedics in the Department of Orthopedics at Rhode Island Hospital/ Warren Alpert Medical School of Brown University in Providence, RI.

Funding

Harvard Clinical and Translational Science CenterUM1TR004408 · NCATS · HARVARD MEDICAL SCHOOL · PI Lindsey Robert Baden, Lee Marshall Nadler · 2023 to 2026
$43.3M
The development of a family navigator intervention and prevention protocol to reduce risk of suicide and self-injurious behavior for youth aged 10 to 14 years.P20GM139664 · NIGMS · RHODE ISLAND HOSPITAL · PI Michael J Mello · 2022 to 2026
$13.3M
Pilot Projects ProgramP30GM122732 · NIGMS · RHODE ISLAND HOSPITAL · PI CRISCO, JOSEPH J · 2017 to 2021
$6.6M
BEAR-MOON: A Two Arm Noninferiority Blinded Randomized Clinical Trial Comparing ACL Repair with BEAR Device vs. Standard of Care Autograft Patellar Tendon ACL ReconstructionR01AR074131 · NIAMS · CLEVELAND CLINIC LERNER COM-CWRU · PI SPINDLER, KURT PAUL · 2018 to 2024
$6.0M
Effects of Intial Graft Tension on ACL Reconstruction (Supplement)R01AR047910 · NIAMS · RHODE ISLAND HOSPITAL (PROVIDENCE, RI) · PI FLEMING, BRADEN C · 2003 to 2013
$4.2M
Knee Arthrosis after ACL Reconstruction: A Long-term Cohort Study with Matched ControlsR01AR074973 · NIAMS · RHODE ISLAND HOSPITAL · PI FLEMING, BRADEN C · 2019 to 2022
$1.3M
Neuromuscular response to competing ACL surgeriesR01AR083168 · NIAMS · RHODE ISLAND HOSPITAL · PI Jillian Elizabeth Beveridge · 2024 to 2026
$1.2M
The Effects of Reduced ACL Stiffness on Dynamic In Vivo Joint FunctionR00AR069094 · NIAMS · RHODE ISLAND HOSPITAL · PI BEVERIDGE, JILLIAN ELIZABETH · 2019 to 2021
$730k
NCATS NIH HHS UM1 TR004408NIAMS NIH HHS R00 AR069094NIAMS NIH HHS R01 AR047910NIAMS NIH HHS R01 AR074131NIAMS NIH HHS R01 AR074973NIAMS NIH HHS R01 AR083168NIGMS NIH HHS P20 GM139664NIGMS NIH HHS P30 GM122732
6 · The paper itself

Abstract

Anterior cruciate ligament (ACL) injury, particularly in increasingly young and active adolescents, continues to pose a clinical challenge with re-injury rates reported as high as 30%. Evidence also suggests that current standard-of-care ACL reconstruction (ACLR) does not mitigate post-traumatic osteoarthritis (PTOA) risk. Bridge- enhanced ACL restoration (BEAR) is a recently developed and tested ACL surgery that promotes primary healing of the native ACL with excellent early results. BEAR has shown to reduce signs of early PTOA compared to ACLR in an animal model. Here, we describe a theoretical framework related to re-innervation that can clarify why the outcomes of ACLR and BEAR surgeries differ. We also discuss how ongoing and new challenges in determining return-to-sport readiness following the competing surgeries may differ, and how emerging imaging tools and measures of neuromuscular function may aid in clinical decision-making to decrease the likelihood of re-injury and PTOA risk.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionAnimalsHumansMechanoreceptorsOsteoarthritis, KneeReturn to SportACLkinematicsneuromuscularpost-traumatic osteoarthritissurgery

Identifiers

PMID39058984
PMCPMC11609849

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.