Evidence map›Paper›PMID 39058595›Full record

ArticleCell reports2024

Ca

Shenyu Zhai, Shintaro Otsuka, Jian Xu, Vernon R J Clarke, Tatiana Tkatch, David Wokosin, Zhong Xie, Asami Tanimura, Hitesh K Agarwal, Graham C R Ellis-Davies and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

  • Update of
    Ca2024
5 · Who and what money

Authors and funding

12 authors.

Shenyu ZhaiDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Shintaro OtsukaDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Jian XuDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Vernon R J ClarkeDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Tatiana TkatchDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
David WokosinDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Zhong XieDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Asami TanimuraDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Hitesh K AgarwalDepartment of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA.
Graham C R Ellis-DaviesDepartment of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA.
Anis ContractorDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
D James SurmeierDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. Electronic address: j-surmeier@northwestern.edu.

Funding

DOPAMINERGIC AND MUSCARINIC SIGNALING IN THE STRIATUMR37NS034696 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DALTON JAMES SURMEIER · 2001 to 2026
$7.3M
PHOTOCHEMICAL REGULATION OF CALCIUM IN CELL PHYSIOLOGYR01GM053395 · NIGMS · OREGON HEALTH AND SCIENCE UNIVERSITY · PI ELLIS-DAVIES, GRAHAM · 1995 to 2020
$6.1M
Light-Driven Control of Neurons in Vitro and in VivoR35NS111600 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Graham Ellis-Davies · 2019 to 2026
$5.5M
The role of glutamate receptors in compulsive and perseverative behaviorR01MH099114 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CONTRACTOR, ANIS · 2012 to 2022
$4.5M
Dopaminergic and Muscarinic Signaling in the StriatumR01NS034696 · NINDS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI SURMEIER, DALTON JAMES · 1996 to 2018
$4.3M
NIGMS NIH HHS R01 GM053395NIMH NIH HHS R01 MH099114NINDS NIH HHS R01 NS034696NINDS NIH HHS R35 NS111600NINDS NIH HHS R37 NS034696
6 · The paper itself

Abstract

Long-term synaptic plasticity at glutamatergic synapses on striatal spiny projection neurons (SPNs) is central to learning goal-directed behaviors and habits. Our studies reveal that SPNs manifest a heterosynaptic, nitric oxide (NO)-dependent form of long-term postsynaptic depression of glutamatergic SPN synapses (NO-LTD) that is preferentially engaged at quiescent synapses. Plasticity is gated by Ca

Indexed as

Cyclic Nucleotide Phosphodiesterases, Type 1Neuronal PlasticityNeuronsSynapsesAnimalsCalciumCorpus StriatumCyclic GMPGlutamic AcidLong-Term Synaptic DepressionMaleMiceMice, Inbred C57BLNitric OxideCalciumCyclic GMPCyclic Nucleotide Phosphodiesterases, Type 1Glutamic AcidNitric OxideautismcGMPCP: Neurosciencelow-threshold spiking interneuronL-type Ca(2+) channelnitric oxideParkinson's diseasephosphodiesterasespiny projection neuronstriatumsynaptic plasticity

Identifiers

PMID39058595
PMCPMC11426333

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.