Evidence map›Paper›PMID 39058300›Full record

Trial reportAging2024

Effectiveness of vaginal probiotics

Yujuan Liu, Xiumiao Zhao, Fei Wu, Jie Chen, Juanzhen Luo, Chunling Wu, Tingtao Chen

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Effectiveness ofThe Journal of international medical research · 2025
    Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Nutrients · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. HPV vaccination associates withFrontiers in microbiology · 2026
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yujuan LiuDepartment of Gynaecology, The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi 330006, People’s Republic of China.
Xiumiao ZhaoQueen Mary School, Nanchang University, Nanchang 330031, People’s Republic of China.
Fei WuDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, People’s Republic of China.
Jie ChenDepartment of Gynaecology, The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi 330006, People’s Republic of China.
Juanzhen LuoDepartment of Gynaecology, The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi 330006, People’s Republic of China.
Chunling WuDepartment of Gynaecology, Jingdezhen Maternal and Child Health Care Hospital, Jingdezhen, Jiangxi 333000, People’s Republic of China.
Tingtao ChenDepartment of Gynaecology, The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi 330006, People’s Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Female genital tract infection with high-risk human papilloma virus (HR-HPV) has the risk of developing into cervical cancer, and there is still a lack of effective therapeutic strategies. Probiotic intervention is considered as a potential intervention for HR-HPV, while exploration into living probiotic preparations for specific diseases remains limited and insufficient. This prospective controlled pilot study was conducted to observe the effect of intravaginal transplantation of a vaginal isolated natural probiotic strain,

Indexed as

Lactobacillus crispatusPapillomavirus InfectionsProbioticsVaginaAdministration, IntravaginalAdultFemaleHumansMicrobiotaMiddle AgedPapillomaviridaePilot ProjectsProspective StudiesViral Loadcervical cancerHR-HPVLactobacillus crispatus chen-01probiotic transplantationvaginal microbiota

Identifiers

PMID39058300
PMCPMC11315381

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.