Evidence map›Paper›PMID 39058279›Full record

ArticleBiochemistry2024

Bioinformatic, Enzymatic, and Structural Characterization of

Zuzanna Dutkiewicz, Annabelle Varrot, Karen J Breese, Keith A Stubbs, Lena Nuschy, Isabella Adduci, Katharina Paschinger, Iain B H Wilson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zuzanna DutkiewiczInstitut für Biochemie, Department für Chemie, Universität für Bodenkultur, Muthgasse 18, Wien 1190, Austria.ORCID 0000-0003-0444-5931
Annabelle VarrotUniv. Grenoble Alpes, CNRS, CERMAV, Grenoble 38000, France.ORCID 0000-0001-6667-8162
Karen J BreeseSchool of Molecular Sciences, University of Western Australia, Crawley, WA 6009, Australia.
Keith A StubbsSchool of Molecular Sciences, University of Western Australia, Crawley, WA 6009, Australia.ORCID 0000-0001-6899-402X
Lena NuschyInstitut für Biochemie, Department für Chemie, Universität für Bodenkultur, Muthgasse 18, Wien 1190, Austria.
Isabella AdduciInstitut für Parasitologie, Department für Pathobiologie, Veterinärmedizinische Universität Wien, Veterinärplatz 1, Wien A-1210, Austria.
Katharina PaschingerInstitut für Biochemie, Department für Chemie, Universität für Bodenkultur, Muthgasse 18, Wien 1190, Austria.ORCID 0000-0002-3594-7136
Iain B H WilsonInstitut für Biochemie, Department für Chemie, Universität für Bodenkultur, Muthgasse 18, Wien 1190, Austria.ORCID 0000-0001-8996-1518

Funding

Austrian Science Fund FWF W 1224
6 · The paper itself

Abstract

Hexosaminidases are key enzymes in glycoconjugate metabolism and occur in all kingdoms of life. Here, we have investigated the phylogeny of the GH20 glycosyl hydrolase family in nematodes and identified a β-hexosaminidase subclade present only in the Dorylaimia. We have expressed one of these, HEX-2 from

Indexed as

Computational BiologyTrichurisAmino Acid SequenceAnimalsbeta-N-AcetylhexosaminidasesCatalytic DomainCrystallography, X-RayHelminth ProteinsHexosaminidasesModels, MolecularMolecular Sequence DataPhylogenySubstrate Specificitybeta-N-AcetylhexosaminidasesHelminth ProteinsHexosaminidases

Identifiers

PMID39058279
PMCPMC11308363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.