Evidence map›Paper›PMID 39058196›Full record

ArticleTropical medicine and infectious disease2024

Investigating the Determinants of Mortality before CD4 Count Recovery in a Cohort of Patients Initiated on Antiretroviral Therapy in South Africa Using a Fine and Gray Competing Risks Model.

Chiedza Elvina Mashiri, Jesca Mercy Batidzirai, Retius Chifurira, Knowledge Chinhamu

Abstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chiedza Elvina MashiriDepartment of Applied Mathematics and Statistics, Midlands State University, Gweru 9055, Zimbabwe.ORCID 0009-0003-2454-3245
Jesca Mercy BatidziraiSchool of Mathematics, Statistics and Computer Science, University of KwaZulu-Natal, Pietermaritzburg Campus, Pietermaritzburg 3209, South Africa.ORCID 0000-0003-3116-1301
Retius ChifuriraSchool of Mathematics, Statistics and Computer Science, University of KwaZulu-Natal, Howard College Campus, Durban 4041, South Africa.
Knowledge ChinhamuSchool of Mathematics, Statistics and Computer Science, University of KwaZulu-Natal, Howard College Campus, Durban 4041, South Africa.ORCID 0000-0003-4296-7677

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD4 count recovery is the main goal for an HIV patient who initiated ART. Early ART initiation in HIV patients can help restore immune function more effectively, even when they have reached an advanced stage. Some patients may respond positively to ART and attain CD4 count recovery. Meanwhile, other patients failing to recover their CD4 count due to non-adherence, treatment resistance and virological failure might lead to HIV-related complications and death. The purpose of this study was to find the determinants of death in patients who failed to recover their CD4 count after initiating antiretroviral therapy. The data used in this study was obtained from KwaZulu-Natal, South Africa, where 2528 HIV-infected patients with a baseline CD4 count of <200 cells/mm

Indexed as

CD4 count recoverycompeting riskcumulative incidenceFine–Gray modelmortality

Identifiers

PMID39058196
PMCPMC11281671

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.