Evidence map›Paper›PMID 39058147›Full record

ArticleToxics2024

Evaluating Molecular Mechanism of Viral Inhibition of Aerosolized Smart Nano-Enabled Antiviral Therapeutic (SNAT) on SARS-CoV-2-Infected Hamsters.

Anais N Bauer, John F Williams, Lok R Pokhrel, Selena Garcia, Niska Majumdar, Jeffrey B Eells, Paul P Cook, Shaw M Akula

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anais N BauerDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
John F WilliamsDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
Lok R PokhrelDepartment of Public Health, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.ORCID 0000-0002-4606-9973
Selena GarciaDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
Niska MajumdarDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
Jeffrey B EellsDepartment of Anatomy and Cell Biology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
Paul P CookDepartment of Internal Medicine, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
Shaw M AkulaDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.

Funding

Janssen (Belgium) TMC114FD2HTX4008North Carolina Biotechnology Center 2021-FLG-3812
6 · The paper itself

Abstract

Smart Nano-enabled Antiviral Therapeutic (SNAT) is a promising nanodrug that previously demonstrated efficacy in preclinical studies to alleviate SARS-CoV-2 pathology in hamsters. SNAT comprises taxoid (Tx)-decorated amino (NH

Indexed as

antiviralmiRNAnanomedicineSARS-CoV-2S proteinvirus

Identifiers

PMID39058147
PMCPMC11280845

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.