Evidence map›Paper›PMID 39057961›Full record

ArticleToxins2024

Citrinin Provoke DNA Damage and Cell-Cycle Arrest Related to Chk2 and FANCD2 Checkpoint Proteins in Hepatocellular and Adenocarcinoma Cell Lines.

Darija Stupin Polančec, Sonja Homar, Daniela Jakšić, Nevenka Kopjar, Maja Šegvić Klarić, Sanja Dabelić

Abstract read
In one paragraph

Article in Toxins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Darija Stupin PolančecOnkoLab Ltd., 10000 Zagreb, Croatia.
Sonja HomarUniversity of Zagreb Faculty of Pharmacy and Biochemistry, Department of Biochemistry and Molecular Biology, 10000 Zagreb, Croatia.
Daniela JakšićUniversity of Zagreb Faculty of Pharmacy and Biochemistry, Department of Microbiology, 10000 Zagreb, Croatia.
Nevenka KopjarMutagenesis Unit, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.ORCID 0000-0002-3117-2847
Maja Šegvić KlarićUniversity of Zagreb Faculty of Pharmacy and Biochemistry, Department of Microbiology, 10000 Zagreb, Croatia.ORCID 0000-0003-1923-6542
Sanja DabelićUniversity of Zagreb Faculty of Pharmacy and Biochemistry, Department of Biochemistry and Molecular Biology, 10000 Zagreb, Croatia.

Funding

This research was funded by strengthening the scientific research and innovation capacities of the Faculty of Pharmacy and Biochemistry, University of Zagreb (FarmInova)financed by the European Regional Development Fund, Operational Program Competitivenes KK.01.1.1.02.0021University of Zagreb support for 2022
6 · The paper itself

Abstract

Citrinin (CIT), a polyketide mycotoxin produced by

Indexed as

Cell Cycle CheckpointsCheckpoint Kinase 2CitrininDNA DamageFanconi Anemia Complementation Group D2 ProteinLiver NeoplasmsA549 CellsAdenocarcinomaCarcinoma, HepatocellularHep G2 CellsHumansCheckpoint Kinase 2CHEK2 protein, humanCitrininFANCD2 protein, humanFanconi Anemia Complementation Group D2 Proteincell-cycle arrestChk2citrinincytotoxicityFANCD2genotoxicityhepatocellular carcinomalung adenocarcinoma

Identifiers

PMID39057961
PMCPMC11281099

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.