Evidence map›Paper›PMID 39057927›Full record

ReviewToxins2024

Cobra Venom Cytotoxins as a Tool for Probing Mechanisms of Mitochondrial Energetics and Understanding Mitochondrial Membrane Structure.

Edward S Gasanoff, Ruben K Dagda

Abstract readReview
In one paragraph

Review in Toxins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Edward S GasanoffSTEM Research Center, Chaoyang Kaiwen Academy, Beijing 100018, China.ORCID 0000-0002-5097-3973
Ruben K DagdaDepartment of Pharmacology, University of Nevada Medical School, Reno, NV 89557, USA.ORCID 0000-0002-9946-9591

Funding

Regulation of Dendrite Homeostasis by PINK1 and PKA in Models of Parkinson's DiseaseR01NS105783 · NINDS · UNIVERSITY OF NEVADA RENO · PI DAGDA, RUBEN K · 2018 to 2022
$1.9M
NIH HHS 2R01NS105783-05NINDS NIH HHS R01 NS105783
6 · The paper itself

Abstract

In this paper, we provide an overview of mitochondrial bioenergetics and specific conditions that lead to the formation of non-bilayer structures in mitochondria. Secondly, we provide a brief overview on the structure/function of cytotoxins and how snake venom cytotoxins have contributed to increasing our understanding of ATP synthesis via oxidative phosphorylation in mitochondria, to reconcile some controversial aspects of the chemiosmotic theory. Specifically, we provide an emphasis on the biochemical contribution of delocalized and localized proton movement, involving direct transport of protons though the F

Indexed as

Elapid VenomsEnergy MetabolismMitochondriaMitochondrial MembranesAdenosine TriphosphateAnimalsCytotoxinsHumansOxidative PhosphorylationAdenosine TriphosphateCytotoxinsElapid VenomsATP synthasebioenergeticscobra venom cytotoxinscytotoxinsneurodegenerationnon-bilayer lipid phaseupdated working model of the chemiosmotic theory

Identifiers

PMID39057927
PMCPMC11281317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.