ReviewPathogens (Basel, Switzerland)2024
Herpes Zoster and Post-Herpetic Neuralgia-Diagnosis, Treatment, and Vaccination Strategies.
Review in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Reciprocal association between neurovascular conflict and trigeminal neuralgia: a systematic review and meta-analysis.Journal of oral & facial pain and headache · 2026Pooled it
- Review of Herpes Zoster Occurrence in Patients With Atopic Dermatitis Treated With JAK Inhibitors.Clinical and translational science · 2026Pooled it
- Exploring the mechanisms and therapeutic role of γ-oryzanol in neuropathic pain: a systematic review.Inflammopharmacology · 2026Pooled it
- Randomized controlled trials of major oral traditional Chinese medicine preparations for postherpetic neuralgia: an evidence map.Frontiers in pharmacology · 2026Pooled it
- Targeting TRPV1 channels: new perspectives on the mechanisms of analgesia for herpes zoster neuralgia and advances in therapeutic research.Frontiers in cellular and infection microbiology · 2026Pooled it
- Current advances in the epidemiology, risk factors, prevention, management, and long-term outcomes of herpes zoster and post-herpetic neuralgia.Frontiers in microbiology · 2026Pooled it
- Application of auricular therapy in postherpetic neuralgia: a scoping review.Frontiers in molecular neuroscience · 2026Pooled it
- Comparative effectiveness of nerve block strategies for preventing postherpetic neuralgia in thoracic herpes zoster: a network meta-analysis.Frontiers in neurology · 2025Pooled it
- Clinical research on traditional Chinese medicine for Postherpetic neuralgia: an evidence map.Frontiers in neurology · 2025Pooled it
- Efficacy and Safety of Dorsal Root Ganglion Pulse Radiofrequency Combined With Sympathetic Radiofrequency Ablation in the Treatment of Acute Herpetic Neuralgia.The Clinical journal of pain · 2026Trial
- Effects of dexmedetomidine nasal spray combined with thoracic paravertebral block on sleep and pain in herpes zoster neuralgia: a randomized controlled trial.BMC anesthesiology · 2026Trial
- Herpes zoster as a vaccine-preventable risk factor increases the risk of dementia: A nested case-control study in Chinese population.Human vaccines & immunotherapeutics · 2026Article
- Efficacy of Ultrasound-Guided Intercostal Nerve Block With Liposomal Bupivacaine for Treating Postherpetic Neuralgia in Adult Patients.The Kaohsiung journal of medical sciences · 2026Article
- Postherpetic neuralgia risk prediction in hospitalised patients with herpes zoster based on MIMIC-IV.Medicine · 2026Article
- Association Between Triglyceride Glucose Index and Postherpetic Neuralgia in Patients with Acute Herpes Zoster: A Retrospective Study.Pain and therapy · 2026Article
- Facial-Stapedial Synkinesis Following Ramsay Hunt Syndrome: A Case Report.Journal of audiology & otology · 2026Article
- Varicella Zoster Virus Infection: Clinical Features, Molecular Pathogenesis, Treatment, and Prevention.MedComm · 2026Review
- Sequential Varicella and Herpes Zoster in an Immunocompetent Adult.Clinical case reports · 2026Article
- [StagingZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026Review
- Epidemiology and risk factors of postherpetic neuralgia worldwide: protocol for a systematic review and meta-analysis.BMJ open · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
introductionHerpes zoster is caused by the reactivation of latent varicella infection within the sensory ganglia, caused by the varicella-zoster virus (VZV). The disease is classically characterized by a painful unilateral vesicular eruption. Complications of the disease include herpes zoster ophthalmicus, Ramsay Hunt syndrome, acute retinal necrosis, and post-herpetic neuralgia. In this paper, we discuss the epidemiology, pathogenesis, clinical features, diagnosis, management, and vaccination strategies of herpes zoster and post-herpetic neuralgia.
methodThis paper was developed with input from specialists from Singapore's public sectors-dermatologists, family physicians, and infectious diseases specialists.
resultsThe diagnosis of herpes zoster is clinical and can be aided with laboratory investigations. Early initiation of antivirals, within 72 h of onset, can reduce the severity and duration of the condition and decrease the intensity of pain. In patients with a high risk of post-herpetic neuralgia, early initiation of anticonvulsants or tricyclic antidepressants can be considered. Herpes zoster is highly preventable, with the advent of the recombinant zoster vaccine (RZV) providing an overall vaccine efficacy of 97.2%. Procedures such as epidural blocks and subcutaneous or intracutaneous injections of local anesthetics and steroids can be considered for patients with a high risk of post-herpetic neuralgia to reduce its incidence.
conclusionThis article serves as a guideline for clinicians in the diagnosis, investigations, management, and prevention of herpes zoster. With the majority of adults in Singapore currently at risk of developing herpes zoster due to varicella immunization being only introduced in 2020, it is important for clinicians to recognize and manage herpes zoster appropriately.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.