Evidence map›Paper›PMID 39057807›Full record

ReviewPathogens (Basel, Switzerland)2024

Grade C Molar-Incisor Pattern Periodontitis in Young Adults: What Have We Learned So Far?

Manuela Maria Viana Miguel, Luciana Macchion Shaddox

Abstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Antimicrobial susceptibility testing ofJournal of oral microbiology · 2026
    Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Manuela Maria Viana MiguelCenter for Oral Health Research, College of Dentistry, University of Kentucky, Lexington, KY 40508, USA.
Luciana Macchion ShaddoxCenter for Oral Health Research, College of Dentistry, University of Kentucky, Lexington, KY 40508, USA.

Funding

Susceptibility Patterns for Grade C Periodontitis in Young IndividualsU01DE031223 · NIDCR · UNIVERSITY OF KENTUCKY · PI Luciana Macchion Shaddox · 2022 to 2026
$6.2M
Mechanisms and Treatment Response of Aggressive Periodontitis in ChildrenR01DE019456 · NIDCR · UNIVERSITY OF FLORIDA · PI AUKHIL, IKRAMUDDIN, SHADDOX, LUCIANA MACCHION · 2009 to 2018
$5.6M
NIDCR NIH HHS R01 DE019456NIDCR NIH HHS U01 DE031223NIH HHS 1U01DE031223 (2022-2027)NIH HHS R01DE019456 (2009-2019)
6 · The paper itself

Abstract

Grade C molar-incisor pattern periodontitis (C-MIP) is a disease that affects specific teeth with an early onset and aggressive progression. It occurs in systemically healthy patients, mostly African descendants, at an early age, with familial involvement, minimal biofilm accumulation, and minor inflammation. Severe and rapidly progressive bone loss is observed around the first molars and incisors. This clinical condition has been usually diagnosed in children and young adults with permanent dentition under 30 years of age. However, this disease can also affect the primary dentition, which is not as frequently discussed in the literature. Radiographic records have shown that most patients diagnosed in the permanent dentition already presented disease signs in the primary dentition. A hyperresponsive immunological profile is observed in local (gingival crevicular fluid-GCF) and systemic environments. Siblings have also displayed a heightened inflammatory profile even without clinical signs of disease.

Indexed as

PeriodontitisAdultAggregatibacter actinomycetemcomitansGingival Crevicular FluidHumansIncisorMolarYoung Adultaggressivegeneticsimmunological factorsmicrobiotaperiodontitis

Identifiers

PMID39057807
PMCPMC11279578

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.