Evidence map›Paper›PMID 39057765›Full record

ArticlePathogens (Basel, Switzerland)2024

The Prevalence of Antibiotic Tolerance in

Margaux Balduck, Akim Strikker, Zina Gestels, Saïd Abdellati, Dorien Van den Bossche, Irith De Baetselier, Chris Kenyon, Sheeba Santhini Manoharan-Basil

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Margaux BalduckSTI Unit, Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium.
Akim StrikkerSTI Unit, Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium.
Zina GestelsSTI Unit, Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium.
Saïd AbdellatiClinical and Reference Laboratory, Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium.ORCID 0000-0002-9620-8257
Dorien Van den BosscheClinical and Reference Laboratory, Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium.
Irith De BaetselierClinical and Reference Laboratory, Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium.ORCID 0000-0002-1804-252X
Chris KenyonSTI Unit, Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium.ORCID 0000-0002-2557-8998
Sheeba Santhini Manoharan-BasilSTI Unit, Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium.ORCID 0000-0001-8421-5137

Funding

PRESTIP Not available
6 · The paper itself

Abstract

backgroundTolerance enables bacteria to survive intermittent antibiotic exposure without an increase in antimicrobial susceptibility. In this study, we investigated the presence of tolerance to three antimicrobials, ceftriaxone, azithromycin and ciprofloxacin, in clinical isolates and the WHO (World Health Organization) reference panel of

methodsWe used the modified tolerance disk (TD test) to assess for tolerance to ceftriaxone, azithromycin and ciprofloxacin in 14 WHO reference strains and 62

resultsA total of 4 of the 62 clinical anorectal isolates and none of the urogenital isolates exhibited tolerance to azithromycin (

conclusionsThis study identified ceftriaxone, azithromycin and ciprofloxacin tolerance in clinical and WHO reference

Indexed as

Anti-Bacterial AgentsAzithromycinCeftriaxoneCiprofloxacinGonorrheaMicrobial Sensitivity TestsNeisseria gonorrhoeaeDrug Resistance, BacterialFemaleHumansMalePrevalenceAnti-Bacterial AgentsAzithromycinCeftriaxoneCiprofloxacinanorectal infectionantimicrobial resistanceazithromycinceftriaxoneciprofloxacinNeisseria gonorrhoeaetoleranceurogenital infection

Identifiers

PMID39057765
PMCPMC11279455

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.