Evidence map›Paper›PMID 39057692›Full record

ArticleMetabolites2024

Impaired Mitochondrial Energy Metabolism Regulated by

Wenyu Gu, Xinli Cong, Yechun Pei, Nuela Manka'a Che Ajuyo, Yi Min, Dayong Wang

Abstract read
In one paragraph

Article in Metabolites, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenyu GuKey Laboratory of Tropical Bioresources of the Educational Ministry of China, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Xinli CongKey Laboratory of Tropical Bioresources of the Educational Ministry of China, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Yechun PeiKey Laboratory of Tropical Bioresources of the Educational Ministry of China, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Nuela Manka'a Che AjuyoKey Laboratory of Tropical Bioresources of the Educational Ministry of China, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Yi MinKey Laboratory of Tropical Bioresources of the Educational Ministry of China, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Dayong WangKey Laboratory of Tropical Bioresources of the Educational Ministry of China, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.ORCID 0000-0002-2086-1663

Funding

National Natural Science Foundation of China 32160214Natural Science Foundation of Hainan Province 821RC1053Natural Science Foundation of Hainan Province 822RC651One Health Cooperative Innovation Center of Hainan University XTCX2022JKB07Postdoctoral Research Funding 323819
6 · The paper itself

Abstract

Alzheimer's disease (AD) is a neurodegenerative disease. Mitochondrial energy metabolism and p70 ribosomal protein S6 kinase (p70S6K) play significant roles in AD pathology. However, the potential relationship between them is unclear. In this study, bioinformatics methods were initially applied to analyze the transcriptomic data in the CA1 and the primary visual cortex of patients with AD and Aβ42-treated SH-SY5Y cells. By applying secreted Aβ42 and

Indexed as

Alzheimer’s diseasemitochondrial energy metabolismoxidative phosphorylationp70S6KRNA sequencingsecreted Aβ42

Identifiers

PMID39057692
PMCPMC11278668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.