Evidence map›Paper›PMID 39057601›Full record

ArticleJournal of the American Society for Mass Spectrometry2024

Numbers of Exchangeable Hydrogens from LC-MS Data of Heavy Water Metabolically Labeled Samples.

Henock M Deberneh, Michael E Taylor, Agnieszka K Borowik, Masaru Miyagi, Benjamin F Miller, Rovshan G Sadygov

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Henock M DebernehDepartment of Biochemistry and Molecular Biology The University of Texas Medical Branch 301 University of Blvd, Galveston, Texas 77555, United States.
Michael E TaylorAging and Metabolism Research Program, Oklahoma Medical Research Foundation 825 NE 13th Street Oklahoma City, Oklahoma 73104, United States.
Agnieszka K BorowikAging and Metabolism Research Program, Oklahoma Medical Research Foundation 825 NE 13th Street Oklahoma City, Oklahoma 73104, United States.ORCID 0000-0002-2208-460X
Masaru MiyagiDepartment of Pharmacology Case Western Reserve University 10900 Euclid Avenue Cleveland, Ohio 44106, United States.
Benjamin F MillerAging and Metabolism Research Program, Oklahoma Medical Research Foundation 825 NE 13th Street Oklahoma City, Oklahoma 73104, United States.
Rovshan G SadygovDepartment of Biochemistry and Molecular Biology The University of Texas Medical Branch 301 University of Blvd, Galveston, Texas 77555, United States.ORCID 0000-0003-1590-155X

Funding

Dissecting the integrated mechanisms of protein turnover to prevent proteostatic decline with agingR01AG074551 · NIA · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI Benjamin Francis Miller · 2022 to 2026
$3.3M
Novel computational methods for in vivo proteome dynamics estimation using heavy water metabolic labeling and LC-MSR01GM112044 · NIGMS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SADYGOV, ROVSHAN G · 2015 to 2023
$2.7M
Protein turnover estimation from fragment ions and precursor enrichment in heavy water labeled LC-MS experimentsR01GM149762 · NIGMS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Rovshan G Sadygov · 2024 to 2026
$1.1M
NIA NIH HHS R01 AG074551NIGMS NIH HHS R01 GM112044NIGMS NIH HHS R01 GM149762
6 · The paper itself

Abstract

Labeling with deuterium oxide (D

Indexed as

Liquid Chromatography-Mass SpectrometryAmino AcidsAnimalsDeuterium OxidePeptidesProteinsAmino AcidsDeuterium OxidePeptidesProteinsheavy water metabolic labelingnumber of deuterium labeling sitesprotein half-lifeprotein turnoverquantification of label enrichmenttime course modeling

Identifiers

PMID39057601
PMCPMC12302360

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.