Evidence map›Paper›PMID 39057340›Full record

ArticleJournal of fungi (Basel, Switzerland)2024

The Mechanosensitive Pkd2 Channel Modulates the Recruitment of Myosin II and Actin to the Cytokinetic Contractile Ring.

Pritha Chowdhury, Debatrayee Sinha, Abhishek Poddar, Madhurya Chetluru, Qian Chen

Abstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Regulation of Yeast Cytokinesis by Calcium.Journal of fungi (Basel, Switzerland) · 2025
    Review
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Pritha ChowdhuryDepartment of Biological Sciences, The University of Toledo, 2801 Bancroft St, Toledo, OH 43606, USA.
Debatrayee SinhaDepartment of Biological Sciences, The University of Toledo, 2801 Bancroft St, Toledo, OH 43606, USA.
Abhishek PoddarDepartment of Biological Sciences, The University of Toledo, 2801 Bancroft St, Toledo, OH 43606, USA.
Madhurya ChetluruDepartment of Biological Sciences, The University of Toledo, 2801 Bancroft St, Toledo, OH 43606, USA.
Qian ChenDepartment of Biological Sciences, The University of Toledo, 2801 Bancroft St, Toledo, OH 43606, USA.

Funding

The mechanism of cell size regulation by polycystinsR01GM144652 · NIGMS · UNIVERSITY OF TOLEDO · PI Qian Chen · 2022 to 2026
$1.6M
National Science Foundation 2144701NIGMS NIH HHS R01 GM144652NIH HHS R01GM144652
6 · The paper itself

Abstract

Cytokinesis, the last step in cell division, separates daughter cells through mechanical force. This is often through the force produced by an actomyosin contractile ring. In fission yeast cells, the ring helps recruit a mechanosensitive ion channel, Pkd2, to the cleavage furrow, whose activation by membrane tension promotes calcium influx and daughter cell separation. However, it is unclear how the activities of Pkd2 may affect the actomyosin ring. Here, through both microscopic and genetic analyses of a hypomorphic

Indexed as

actincytokinesisfission yeastmyosinPkd2polycystin

Identifiers

PMID39057340
PMCPMC11277609

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.