Evidence map›Paper›PMID 39057310›Full record

ArticleJournal of functional biomaterials2024

Electrophoretic Deposition of Chitosan Coatings on the Porous Titanium Substrate.

Julia Flesińska, Magdalena Szklarska, Izabela Matuła, Adrian Barylski, Sylwia Golba, Julia Zając, Maciej Gawlikowski, Przemysław Kurtyka, Barbara Ilnicka, Grzegorz Dercz

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Julia FlesińskaInstitute of Materials Engineering, University of Silesia in Katowice, 75 Pułku Piechoty St. 1 A, 41-500 Chorzów, Poland.ORCID 0009-0002-3905-2185
Magdalena SzklarskaInstitute of Materials Engineering, University of Silesia in Katowice, 75 Pułku Piechoty St. 1 A, 41-500 Chorzów, Poland.ORCID 0000-0001-8716-630X
Izabela MatułaInstitute of Materials Engineering, University of Silesia in Katowice, 75 Pułku Piechoty St. 1 A, 41-500 Chorzów, Poland.ORCID 0000-0001-8013-7776
Adrian BarylskiInstitute of Materials Engineering, University of Silesia in Katowice, 75 Pułku Piechoty St. 1 A, 41-500 Chorzów, Poland.ORCID 0000-0002-1863-1471
Sylwia GolbaInstitute of Materials Engineering, University of Silesia in Katowice, 75 Pułku Piechoty St. 1 A, 41-500 Chorzów, Poland.ORCID 0000-0003-4550-0490
Julia ZającInstitute of Materials Engineering, University of Silesia in Katowice, 75 Pułku Piechoty St. 1 A, 41-500 Chorzów, Poland.ORCID 0009-0008-0344-7592
Maciej GawlikowskiFoundation of Cardiac Surgery Development, Institute of Heart Prostheses, 35a Wolności St., 41-800 Zabrze, Poland.
Przemysław KurtykaFoundation of Cardiac Surgery Development, Institute of Heart Prostheses, 35a Wolności St., 41-800 Zabrze, Poland.ORCID 0000-0001-8692-0737
Barbara IlnickaFaculty of Automatic Control, Electronics and Computer Science, Silesian University of Technology, Akademicka 16 St., 44-100 Gliwice, Poland.
Grzegorz DerczInstitute of Materials Engineering, University of Silesia in Katowice, 75 Pułku Piechoty St. 1 A, 41-500 Chorzów, Poland.ORCID 0000-0003-3682-7184

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medicine is looking for solutions to help implant patients recover more smoothly. The porous implants promote osteointegration, thereby providing better stabilization. Introducing porosity into metallic implants enhances their biocompatibility and facilitates osteointegration. The introduction of porosity is also associated with a reduction in Young's modulus, which reduces the risk of tissue outgrowth around the implant. However, the risk of chronic inflammation remains a concern, necessitating the development of coatings to mitigate adverse reactions. An interesting biomaterial for such modifications is chitosan, which has antimicrobial, antifungal, and osteointegration properties. In the present work, a porous titanium biomaterial was obtained by powder metallurgy, and electrophoretic deposition of chitosan coatings was used to modify its surface. This study investigated the influence of ethanol content in the deposition solution on the quality of chitosan coatings. The EPD process facilitates the control of coating thickness and morphology, with higher voltages resulting in thicker coatings and increased pore formation. Ethanol concentration in the solution affects coating quality, with higher concentrations leading to cracking and peeling. Optimal coating conditions (30 min/10 V) yield high-quality coatings, demonstrating excellent cell viability and negligible cytotoxicity. The GIXD and ATR-FTIR analysis confirmed the presence of deposited chitosan coatings on Ti substrates. The microstructure of the chitosan coatings was examined by scanning electron microscopy. Biological tests showed no cytotoxicity of the obtained materials, which allows for further research and the possibility of their use in medicine. In conclusion, EPD offers a viable method for producing chitosan-based coatings with controlled properties for biomedical applications, ensuring enhanced patient outcomes and implant performance.

Indexed as

chitosanelectrophoretic depositionporous titanium

Identifiers

PMID39057310
PMCPMC11277708

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.