Evidence map›Paper›PMID 39057175›Full record

ArticleCurrent oncology (Toronto, Ont.)2024

Addressing the Rising Trend in Early-Age-Onset Cancers in Canada.

Petra Wildgoose, Filomena Servidio-Italiano, Michael J Raphael, Monika Slovinec D'Angelo, Cassandra Macaulay, Shaqil Kassam, Nancy Nixon, José Perea, Sarah Hamilton, Ravi Ramjeesingh and 5 more

Abstract readConference Proceedings
In one paragraph

Article in Current oncology (Toronto, Ont.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Petra WildgooseSunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.
Filomena Servidio-ItalianoColorectal Cancer Resource & Action Network (CCRAN), Toronto, ON M4W 3E2, Canada.
Michael J RaphaelSunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.
Monika Slovinec D'AngeloColorectal Cancer Resource & Action Network (CCRAN), Toronto, ON M4W 3E2, Canada.
Cassandra MacaulayColorectal Cancer Resource & Action Network (CCRAN), Toronto, ON M4W 3E2, Canada.
Shaqil KassamSouthlake Stronach Regional Cancer Centre, Newmarket, ON L3Y 2P9, Canada.
Nancy NixonTom Baker Cancer Centre, Calgary, AB T2N 4N2, Canada.
José PereaDepartment of Medicine, Institute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.ORCID 0000-0001-5522-8844
Sarah HamiltonBC Cancer Agency, Vancouver, BC V5Z 4E6, Canada.
Ravi RamjeesinghNova Scotia Cancer Centre, Dalhousie University, Halifax, NS B3H 1V8, Canada.ORCID 0000-0001-5584-3505
Sharlene GillBC Cancer Agency, Vancouver, BC V5Z 4E6, Canada.ORCID 0000-0003-3306-3617
Aaron PollettDivision of Diagnostic Medical Genetics, Mount Sinai Hospital, Toronto, ON M5G 1X5, Canada.
Shuji OginoDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-3909-2323
Tomotaka UgaiDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA 02115, USA.
Abha GuptaAdolescent & Young Adult (AYA) Oncology Program, Princess Margaret Hospital, Toronto, ON M5G 2M9, Canada.

Funding

Integration of Immunology and Microbiology into Molecular Pathological Epidemiology of Colorectal CancerR50CA274122 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI UGAI, TOMOTAKA · 2023 to 2025
$506k
Cancer Research UK 27140NCI NIH HHS R50 CA274122
6 · The paper itself

Abstract

A multi-disciplinary symposium on early-age onset cancer (EAOC) was held in October 2023 to explore challenges experienced by this rapidly growing population. A major outcome of the symposium was recognition of the remarkable similarities of EAOC patients' journeys across cancer sites. Prevention and early detection of cancer are hindered by a lack of awareness among patients and family doctors that cancer can and does occur in younger persons. Distinct characteristics of the disease-such as a later stage at diagnosis and more aggressive tumor biology-require more potent treatments, which result in profound physical and psychosocial consequences that are unique to this age group. EAOC patient empowerment emerged as another key theme of the symposium. The development of a greater number of specialized clinics was called for, and patient support groups were recognized for the vital role they play in empowering patients and their families. Leading-edge medical advancements hold tremendous hope across the spectrum of EAOC care. New technologies based on genomic profiling, immunotherapy and microbiome alteration contribute to the development of highly effective, personalized approaches to treatment. All symposium participants expressed their commitment to speak with one resounding voice to advocate for equitable access to leading care practices for EAOC patients; thus, a fourth symposium is planned for November 2024.

Indexed as

NeoplasmsAge of OnsetCanadaHumansEAOCEAOCRCearly age onset canceryoung onset cancer

Identifiers

PMID39057175
PMCPMC11276492

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.