Evidence map›Paper›PMID 39057171›Full record

ArticleCurrent oncology (Toronto, Ont.)2024

Canadian Consensus for Treatment of BRAF

Craig Erker, Magimairajan Issai Vanan, Valérie Larouche, Liana Nobre, Chantel Cacciotti, Stéphanie Vairy, Shayna Zelcer, Adam Fleming, Eric Bouffet, Nada Jabado and 18 more

Abstract readConsensus Statement
In one paragraph

Article in Current oncology (Toronto, Ont.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Advances in the management of pediatric low-grade glioma.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Review
  5. Review
  6. RAS/MAPK inhibition in pediatric gliomas.Neuro-oncology advances · 2026
    Review
  7. Dabrafenib in pediatric patients withNeuro-oncology practice · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Craig ErkerDepartment of Pediatrics, Dalhousie University, Halifax, NS B3H 4R2, Canada.ORCID 0000-0003-1394-7167
Magimairajan Issai VananPediatric Neuro-Oncology, Division of Pediatric Hematology-Oncology and BMT, Cancer Care Manitoba, 3a Department of Pediatrics and Child Health, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.ORCID 0000-0003-2015-0615
Valérie LaroucheDepartment of Pediatric Hemato-Oncology, CHU de Québec-Université Laval, Quebec City, QC G1V 4G2, Canada.ORCID 0000-0002-9773-0995
Liana NobreDepartment of Pediatrics, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Chantel CacciottiDivision of Hematology/Oncology, Department of Pediatrics, London Health Sciences Centre & Western University, London, ON N6A 5A5, Canada.
Stéphanie VairyDepartment of Pediatrics, Division of Pediatric Hematology, CHU Sherbrooke, QC J1H 5N4, Canada.ORCID 0000-0001-8107-9969
Shayna ZelcerDivision of Hematology/Oncology, Department of Pediatrics, London Health Sciences Centre & Western University, London, ON N6A 5A5, Canada.
Adam FlemingMcMaster Children's Hospital, Hamilton, ON L8N 3Z5, Canada.ORCID 0000-0002-7194-3220
Eric BouffetDepartment of Pediatrics, University of Toronto, Toronto, ON M5S 1A1, Canada.ORCID 0000-0002-6832-6539
Nada JabadoMontreal Children's Hospital, Montréal, QC H4A 3J1, Canada.ORCID 0000-0003-2485-3692
Geneviève LegaultMontreal Children's Hospital, Montréal, QC H4A 3J1, Canada.
Samuele RenziDepartment of Pediatric Hemato-Oncology, CHU de Québec-Université Laval, Quebec City, QC G1V 4G2, Canada.
Tara McKeownDepartment of Pediatrics, University of Toronto, Toronto, ON M5S 1A1, Canada.
Bruce CrooksDepartment of Pediatrics, Dalhousie University, Halifax, NS B3H 4R2, Canada.ORCID 0000-0003-4715-4536
Nirav ThackerDivision of Hematology/Oncology, CHEO, Ottawa, ON K1H 8L1, Canada.
Vijay RamaswamyDepartment of Pediatrics, University of Toronto, Toronto, ON M5S 1A1, Canada.ORCID 0000-0002-6557-895X
Hallie ColtinDivision of Hematology Oncology, CHU Sainte-Justine, Montréal, QC H3T 1C5, Canada.
Lucie Lafay-CousinAlberta Children's Hospital, Calgary, AB T3B 6A8, Canada.
Sylvia ChengB.C. Children's Hospital, Vancouver, BC V6H 3N1, Canada.
Juliette HukinB.C. Children's Hospital, Vancouver, BC V6H 3N1, Canada.
Seth Andrew ClimansDepartment of Oncology, Western University, London, ON N6A 3K7, Canada.ORCID 0000-0002-4961-237X
Mary Jane Lim-FatOdette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON M5S 1A1, Canada.
Sarah McKillopWomen and Children's Health Research Institute, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Sarah LapointeDivision of Neurology, Department of Neurosciences, Montreal, QC H3A 2B4, Canada.
Mélanie AlvesDepartment of Neurosciences, University of Montreal, Montréal, QC H3T 1J4, Canada.
Julie BennettDepartment of Pediatrics, University of Toronto, Toronto, ON M5S 1A1, Canada.
Uri TaboriDepartment of Pediatrics, University of Toronto, Toronto, ON M5S 1A1, Canada.
Sébastien PerreaultDepartment of Neurosciences, University of Montreal, Montréal, QC H3T 1J4, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

GliomaMutationProto-Oncogene Proteins B-rafAdolescentBrain NeoplasmsCanadaChildFemaleHumansMaleProtein Kinase InhibitorsYoung AdultBRAF protein, humanProtein Kinase InhibitorsProto-Oncogene Proteins B-rafBRAF inhibitorBRAF V600E mutationgliomahigh-grade gliomaMEK inhibitorpediatric low-grade glioma

Identifiers

PMID39057171
PMCPMC11276207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.