Evidence map›Paper›PMID 39057138›Full record

ReviewCurrent oncology (Toronto, Ont.)2024

Integrating Molecular Insights into Biliary Tract Cancer Management: A Review of Personalized Therapeutic Strategies.

Mar Ros-Buxó, Ezequiel Mauro, Tamara Sauri, Gemma Iserte, Carla Fuster-Anglada, Alba Díaz, Laura Sererols-Viñas, Silvia Affo, Alejandro Forner

Abstract readReview
In one paragraph

Review in Current oncology (Toronto, Ont.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mar Ros-BuxóSchool of Medicine, Universitat de Barcelona, 08007 Barcelona, Spain.
Ezequiel MauroSchool of Medicine, Universitat de Barcelona, 08007 Barcelona, Spain.ORCID 0000-0002-0757-7676
Tamara SauriSchool of Medicine, Universitat de Barcelona, 08007 Barcelona, Spain.ORCID 0000-0002-7479-5120
Gemma IserteInstitut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
Carla Fuster-AngladaInstitut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
Alba DíazSchool of Medicine, Universitat de Barcelona, 08007 Barcelona, Spain.ORCID 0000-0002-0456-7085
Laura Sererols-ViñasInstitut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.ORCID 0009-0001-4025-0288
Silvia AffoInstitut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.ORCID 0000-0002-9731-3913
Alejandro FornerSchool of Medicine, Universitat de Barcelona, 08007 Barcelona, Spain.ORCID 0000-0002-9014-4950

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biliary tract cancers (BTCs) are rare and aggressive malignancies with an increasing incidence and poor prognosis. The standard systemic treatment for BTCs has evolved to include immune checkpoint inhibitors associated with gemcitabine-cisplatin as first-line therapies. However, survival rates remain low, highlighting the critical need for personalized treatment strategies based on molecular profiling. Currently, significant advancements have been made in the molecular characterization of BTCs, where genetic alterations, such as

Indexed as

Biliary Tract NeoplasmsPrecision MedicineHumansMolecular Targeted TherapyBRAFBTCcholangiocarcinomaESCATFGFR2IDH1KRASliver transplantationmolecular profileNTRK

Identifiers

PMID39057138
PMCPMC11275621

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.