Evidence map›Paper›PMID 39056862›Full record

ArticleBiomimetics (Basel, Switzerland)2024

Enhancing Interpretability in Medical Image Classification by Integrating Formal Concept Analysis with Convolutional Neural Networks.

Minal Khatri, Yanbin Yin, Jitender Deogun

Abstract read
In one paragraph

Article in Biomimetics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Minal KhatriDepartment of Computer Science and Engineering, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.ORCID 0000-0003-1060-5196
Yanbin YinDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.ORCID 0000-0001-7667-881X
Jitender DeogunDepartment of Computer Science and Engineering, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.ORCID 0000-0001-6402-2549

Funding

Exploration of cloud computing for CAZyme researchR01GM140370 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI YIN, YANBIN · 2021 to 2024
$1.5M
Bioinformatics Discovery of Anti-CRISPR Operons in Human Gut MicrobiomeR21AI171952 · NIAID · UNIVERSITY OF NEBRASKA LINCOLN · PI YIN, YANBIN · 2022 to 2023
$401k
NIAID NIH HHS R21 AI171952NIGMS NIH HHS R01 GM140370
6 · The paper itself

Abstract

In this study, we present a novel approach to enhancing the interpretability of medical image classification by integrating formal concept analysis (FCA) with convolutional neural networks (CNNs). While CNNs are increasingly applied in medical diagnoses, understanding their decision-making remains a challenge. Although visualization techniques like saliency maps offer insights into CNNs' decision-making for individual images, they do not explicitly establish a relationship between the high-level features learned by CNNs and the class labels across entire dataset. To bridge this gap, we leverage the FCA framework as an image classification model, presenting a novel method for understanding the relationship between abstract features and class labels in medical imaging. Building on our previous work, which applied this method to the MNIST handwritten image dataset and demonstrated that the performance is comparable to CNNs, we extend our approach and evaluation to histopathological image datasets, including Warwick-QU and BreakHIS. Our results show that the FCA-based classifier offers comparable accuracy to deep neural classifiers while providing transparency into the classification process, an important factor in clinical decision-making.

Indexed as

BreakHISCNNFCAhistopathologyinterpretabilityWarwick-QU

Identifiers

PMID39056862
PMCPMC11274788

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.