Evidence map›Paper›PMID 39056762›Full record

ReviewCells2024

Managing Patients with Hypereosinophilic Syndrome: A Statement from the Italian Society of Allergy, Asthma, and Clinical Immunology (SIAAIC).

Marco Caminati, Luisa Brussino, Matilde Carlucci, Palma Carlucci, Lucia Federica Carpagnano, Cristiano Caruso, Lorenzo Cosmi, Simona D'Amore, Stefano Del Giacco, Aikaterini Detoraki and 22 more

Abstract readReview
In one paragraph

Review in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Hypereosinophilia: clinical and therapeutic approach in 2025.Current opinion in allergy and clinical immunology · 2025
    Review
  10. Article
  11. Biologic Agents in Idiopathic Hypereosinophilic Syndrome.Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Marco CaminatiAsthma Centre and Allergy Unit, Center for Hypereosinophilic Dysimmune Diseases, Department of Medicine, University of Verona, 37124 Verona, Italy.ORCID 0000-0001-7383-1487
Luisa BrussinoSSDDU Immunologia Clinica ed Allergologia, AO Mauriziano, 10128 Turin, Italy.ORCID 0000-0001-7249-7616
Matilde CarlucciHealth Directorate, Verona Integrated University Hospital, 35134 Verona, Italy.
Palma CarlucciDepartment of Emergency and Organ Transplantation, School of Allergology and Clinical Immunology, University of Bari Aldo Moro, 70126 Bari, Italy.ORCID 0000-0001-7661-0866
Lucia Federica CarpagnanoDepartment of Diagnostics and Public Health, University of Verona, 37126 Verona, Italy.
Cristiano CarusoAllergologia dell'Istituto di Clinica Medica del Policlinico Gemelli, Università Cattolica di Roma, 00168 Rome, Italy.ORCID 0000-0001-7631-029X
Lorenzo CosmiDepartment Experimental and Clinical Medicine, University of Florence, 50121 Florence, Italy.ORCID 0000-0002-8150-8177
Simona D'AmoreDepartment of Precision and Regenerative Medicine and Ionian Area, UOC Medicina Interna "Guido Baccelli", University of Bari Aldo Moro, Policlinico, 70126 Bari, Italy.ORCID 0000-0002-5432-8808
Stefano Del GiaccoDepartment of Medical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.
Aikaterini DetorakiDivision of Internal Medicine and Clinical Immunology, Department of Internal Medicine and Clinical Complexity University of Naples Federico II, 80138 Naples, Italy.ORCID 0000-0002-3692-1384
Mario Di GioacchinoCenter for Advanced Studies and Technology (CAST), G. D'Annunzio University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-9224-5886
Andrea MatucciImmunoallergology Unit, Careggi University Hospital, 50134 Florence, Italy.
Ilaria MormileDepartment of Translational Medical Sciences, Federico II University, 80131 Naples, Italy.ORCID 0000-0001-7599-5426
Francescopaolo GranataDepartment of Translational Medical Sciences, Federico II University, 80131 Naples, Italy.ORCID 0000-0002-2793-8889
Gabriella GuarnieriDepartment of Engineering for Innovation Medicine, Section of Innovation Biomedicine, Hematology Area, University of Verona, 37129 Verona, Italy.
Mauro KramperaDepartment of Engineering for Innovation Medicine, Section of Innovation Biomedicine, Hematology Area, University of Verona, 37129 Verona, Italy.ORCID 0000-0002-7280-2040
Matteo MauleAsthma Centre and Allergy Unit, Center for Hypereosinophilic Dysimmune Diseases, Department of Medicine, University of Verona, 37124 Verona, Italy.
Eustachio NettisDepartment of Emergency and Organ Transplantation, School of Allergology and Clinical Immunology, University of Bari Aldo Moro, 70126 Bari, Italy.
Stefania NicolaSSDDU Immunologia Clinica ed Allergologia, AO Mauriziano, 10128 Turin, Italy.
Silvia NovielloDepartment of Precision and Regenerative Medicine and Ionian Area, UOC Medicina Interna "Guido Baccelli", University of Bari Aldo Moro, Policlinico, 70126 Bari, Italy.
Fabrizio PaneDepartment of Clinical Medicine and Surgery, University Federico II, 80138 Naples, Italy.ORCID 0000-0003-2563-4125
Cristina PapayannidisIRCCS Azienda Ospedaliero-Universitaria Di Bologna, Istituto Di Ematologia "Seràgnoli", 40126 Bologna, Italy.
Paola ParronchiDepartment Experimental and Clinical Medicine, University of Florence, 50121 Florence, Italy.ORCID 0000-0002-9184-5089
Girolamo PelaiaDepartment of Health Sciences, University "Magna Graecia" of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0001-9288-8913
Erminia RidoloDepartment of Clinical and Experimental Medicine, University of Parma, 43124 Parma, Italy.
Francesca Wanda RossiDepartment of Translational Medical Sciences, Federico II University, 80131 Naples, Italy.ORCID 0000-0002-5430-032X
Gianenrico SennaAsthma Centre and Allergy Unit, Center for Hypereosinophilic Dysimmune Diseases, Department of Medicine, University of Verona, 37124 Verona, Italy.ORCID 0000-0003-4172-3216
Massimo TriggianiDivision of Allergy and Clinical Immunology, University of Salerno, 84084 Fisciano, Italy.ORCID 0000-0001-7318-2093
Angelo VaccaDepartment of Precision and Regenerative Medicine and Ionian Area, UOC Medicina Interna "Guido Baccelli", University of Bari Aldo Moro, Policlinico, 70126 Bari, Italy.ORCID 0000-0002-4567-8216
Emanuele VivarelliDepartment of Biomedicine, Azienda Ospedaliero Universitaria Careggi, 50134 Florence, Italy.
Alessandra VultaggioDepartment of Biomedicine, Azienda Ospedaliero Universitaria Careggi, 50134 Florence, Italy.ORCID 0000-0002-8775-9217
Amato de PaulisDepartment of Translational Medical Sciences, Federico II University, 80131 Naples, Italy.ORCID 0000-0003-0347-2540

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypereosinophilic syndrome (HES) encompasses a heterogeneous and complex group of different subtypes within the wider group of hypereosinophilic disorders. Despite increasing research interest, several unmet needs in terms of disease identification, pathobiology, phenotyping, and personalized treatment remain to be addressed. Also, the prospective burden of non-malignant HES and, more in general, HE disorders is currently unknown. On a practical note, shortening the diagnostic delay and the time to an appropriate treatment approach probably represents the most urgent issue, even in light of the great impact of HES on the quality of life of affected patients. The present document represents the first action that the Italian Society of Allergy, Asthma, and Clinical Immunology (SIAAIC) has finalized within a wider project aiming to establish a collaborative national network on HES (InHES-Italian Network on HES) for patients and physicians. The first step of the project could not but focus on defining a common language as well as sharing with all of the medical community an update on the most recent advances in the field. In fact, the existing literature has been carefully reviewed in order to critically integrate the different views on the topic and derive practical recommendations on disease identification and treatment approaches.

Indexed as

Hypereosinophilic SyndromeAllergy and ImmunologyAsthmaDisease ManagementHumansItalyQuality of LifeSocieties, Medicaleosinophilshypereosinophiliahypereosinophilic syndromemanagementmepolizumabnetworkprecision medicine

Identifiers

PMID39056762
PMCPMC11274683

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.