Evidence map›Paper›PMID 39056721›Full record

ArticleBiology2024

Retrospective Single-Center Case Study of Clinical Variables and the Degree of Actinic Elastosis Associated with Rare Skin Cancers.

Konstantin Drexler, Lara Bollmann, Sigrid Karrer, Mark Berneburg, Sebastian Haferkamp, Dennis Niebel

Abstract read
In one paragraph

Article in Biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Konstantin DrexlerDepartment of Dermatology, University Medical Center Regensburg, 93053 Regensburg, Germany.ORCID 0009-0004-6601-6299
Lara BollmannDepartment of Dermatology, University Medical Center Regensburg, 93053 Regensburg, Germany.
Sigrid KarrerDepartment of Dermatology, University Medical Center Regensburg, 93053 Regensburg, Germany.
Mark BerneburgDepartment of Dermatology, University Medical Center Regensburg, 93053 Regensburg, Germany.
Sebastian HaferkampDepartment of Dermatology, University Medical Center Regensburg, 93053 Regensburg, Germany.ORCID 0000-0002-3894-8345
Dennis NiebelDepartment of Dermatology, University Medical Center Regensburg, 93053 Regensburg, Germany.ORCID 0000-0003-2069-0486

Funding

Konstantin Drexler is a collegiate member of "Else-Kröner-Fresenius-Stiftung" and a member of the "BZKF Young Scientist Fellowship". 1234
6 · The paper itself

Abstract

(1) Background: Rare skin cancers include epithelial, neuroendocrine, and hematopoietic neoplasias as well as cutaneous sarcomas. Ultraviolet (UV) radiation and sunburns are important drivers for the incidence of certain cutaneous sarcomas; however, the pathogenetic role of UV light is less clear in rare skin cancers compared to keratinocyte cancer and melanoma. In this study, we compared the degree of actinic elastosis (AE) as a surrogate for lifetime UV exposure among selected rare skin cancers (atypical fibroxanthoma [AFX], pleomorphic dermal sarcoma [PDS], dermatofibrosarcoma protuberans [DFSP], Kaposi sarcoma [KS], Merkel cell carcinoma [MCC], and leiomyosarcoma [LMS]) while taking into account relevant clinical variables (age, sex, and body site). (2) Methods: We newly established a semi-quantitative score for the degree of AE ranging from 0 = none to 3 = total loss of elastic fibers (basophilic degeneration) and multiplied it by the perilesional vertical extent (depth), measured histometrically (tumor-associated elastosis grade (TEG)). We matched the TEG of

Indexed as

atypical fibroxanthomadermatofibrosarcoma protuberansKaposi sarcomaleiomyosarcomaMerkel cell carcinomapleomorphic dermal sarcoma

Identifiers

PMID39056721
PMCPMC11274094

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.