Bone Incorporation of a Poly (L-Lactide-Co-D, L-Lactide) Internal Fixation Device in a Rat's Tibia: Microtomographic, Confocal LASER, and Histomorphometric Analysis.
Article in Biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1citing papers in PubMed
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1 · What the graph read from it
What it found
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2 · The registry
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5 · Who and what money
Authors and funding
16 authors.
Harrisson Lucho Mamani-ValerianoDepartment of Diagnosis and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16010-380, SP, Brazil.ORCID 0000-0003-0465-1399
Nelson Padilha SilvaDepartment of Diagnosis and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16010-380, SP, Brazil.
Heloisa Helena NímiaDepartment of Dental Materials and Prothesis, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16010-380, SP, Brazil.ORCID 0000-0002-4645-8768
Maísa Pereira-SilvaDepartment of Diagnosis and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16010-380, SP, Brazil.ORCID 0000-0003-2483-8695
Maria Eduarda de Freitas Santana OliveiraDepartment of Diagnosis and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16010-380, SP, Brazil.ORCID 0000-0002-4074-4288
Letícia Gabriella de Souza RodriguesDepartment of Diagnosis and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16010-380, SP, Brazil.
Paulo Matheus Honda TavaresDepartment of Diagnosis and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16010-380, SP, Brazil.ORCID 0000-0002-8190-4217
Henrique HadadDepartment of Diagnosis and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16010-380, SP, Brazil.ORCID 0000-0001-6446-3643
Laís Kawamata de JesusDepartment of Diagnosis and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16010-380, SP, Brazil.ORCID 0000-0002-0459-5860
Ana Flávia Piquera SantosDepartment of Diagnosis and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16010-380, SP, Brazil.ORCID 0000-0001-7562-772X
Débora de Barros BarbosaDepartment of Dental Materials and Prothesis, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16010-380, SP, Brazil.ORCID 0000-0002-3623-5093
Pier Paolo PoliImplant Center for Edentulism and Jawbone Atrophies, Maxillofacial Surgery and Odontostomatology Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0003-3739-1490
Carlo MaioranaImplant Center for Edentulism and Jawbone Atrophies, Maxillofacial Surgery and Odontostomatology Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Paulo Sergio Perri de CarvalhoImplant Dentistry Postgraduate Program, São Leopoldo Mandic School of Dentistry and Research Center, Campinas 13045-755, SP, Brazil.
Roberta OkamotoDepartment of Basic Sciences, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16015-253, SP, Brazil.ORCID 0000-0002-6773-6966
Francisley Ávila SouzaDepartment of Diagnosis and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16010-380, SP, Brazil.ORCID 0000-0002-1427-071X
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
This study evaluated the bone incorporation process of a screw-shaped internal fixation device made of poly (L-lactide-co-D, L-lactide) (PLDLLA). Thirty-two male Wistar rats received 32 fixation devices (2 mm × 6 mm) randomly assigned to either the right or left tibia and one implant in each animal. After 7, 14, 28, and 42 days, the rats were euthanized and the specimens were subjected to microtomographic computed tomography (microCT) and histomorphometric analyses to evaluate bone interface contact (BIC%) and new bone formation (NBF%) in cortical and cancellous bone areas. The animals euthanized on days 28 and 42 were treated with calcein and alizarin red, and confocal LASER microscopy was performed to determine the mineral apposition rate (MAR). Micro-CT revealed a higher percentage of bone volume (
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Bone Incorporation of a Poly (L-Lactide-Co-D, L-Lactide) Internal Fixation Device in a Rat's Tibia: Microtomographic, Confocal LASER, and Histomorphometric Analysis. · full record | OpenQuestion