Evidence map›Paper›PMID 39056595›Full record

ArticleBiosensors2024

Copolymer-Coated Gold Nanoparticles: Enhanced Stability and Customizable Functionalization for Biological Assays.

Dario Brambilla, Federica Panico, Lorenzo Zarini, Alessandro Mussida, Anna M Ferretti, Mete Aslan, M Selim Ünlü, Marcella Chiari

Abstract read
In one paragraph

Article in Biosensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dario BrambillaInstitute of Chemical and Technological Science "Giulio Natta", National Research Council of Italy, Via Privata Mario Bianco 9, 20131 Milan, Italy.ORCID 0000-0003-3490-4481
Federica PanicoInstitute of Chemical and Technological Science "Giulio Natta", National Research Council of Italy, Via Privata Mario Bianco 9, 20131 Milan, Italy.
Lorenzo ZariniInstitute of Chemical and Technological Science "Giulio Natta", National Research Council of Italy, Via Privata Mario Bianco 9, 20131 Milan, Italy.ORCID 0009-0008-0082-2289
Alessandro MussidaInstitute of Chemical and Technological Science "Giulio Natta", National Research Council of Italy, Via Privata Mario Bianco 9, 20131 Milan, Italy.ORCID 0009-0001-4611-0497
Anna M FerrettiInstitute of Chemical and Technological Science "Giulio Natta", National Research Council of Italy, Via Gaudenzio Fantoli 16/15, 20138 Milan, Italy.ORCID 0000-0002-7373-7965
Mete AslanElectrical and Computer Engineering Department, Boston University, Boston, MA 02215, USA.
M Selim ÜnlüElectrical and Computer Engineering Department, Boston University, Boston, MA 02215, USA.ORCID 0000-0002-8594-892X
Marcella ChiariInstitute of Chemical and Technological Science "Giulio Natta", National Research Council of Italy, Via Privata Mario Bianco 9, 20131 Milan, Italy.ORCID 0000-0002-4670-1430

Funding

HORIZON-EIC-2021-TRANSITIONOPEN-01 101058200
6 · The paper itself

Abstract

Gold nanoparticles (AuNPs) play a vital role in biotechnology, medicine, and diagnostics due to their unique optical properties. Their conjugation with antibodies, antigens, proteins, or nucleic acids enables precise targeting and enhances biosensing capabilities. Functionalized AuNPs, however, may experience reduced stability, leading to aggregation or loss of functionality, especially in complex biological environments. Additionally, they can show non-specific binding to unintended targets, impairing assay specificity. Within this work, citrate-stabilized and silica-coated AuNPs (GNPs and SiGNPs, respectively) have been coated using

Indexed as

GoldMetal NanoparticlesPolymersAcrylamidesBiological AssayBiosensing TechniquesSilicon DioxideStreptavidinAcrylamidesGoldPolymersSilicon DioxideStreptavidinbioassaybiomolecule functionalizationcoatingDNAgold nanoparticlesmicroarraypolymerstreptavidin

Identifiers

PMID39056595
PMCPMC11274550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.