Evidence map›Paper›PMID 39056201›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2024

Prevalence of chronic hepatitis C infection in the general population: results from a national survey, Estonia, July to December 2022.

Mira Hleyhel, Julia Geller, Amal Sadou, Paul Naaber, Tatiana Kuznetsova, Sigrid Vorobjov, Marleen Lõhmus, Martina Furegato, Suzanne Reed, Benjamin Bluemel and 2 more

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Towards eliminating hepatitis C as a public health threat: different speeds, different needs.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mira HleyhelCerner Enviza/Oracle Life Sciences, Paris, France.
Julia GellerNational Institute for Health Development, Tallinn, Estonia.
Amal SadouCerner Enviza/Oracle Life Sciences, Paris, France.
Paul NaaberInstitute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
Tatiana KuznetsovaNational Institute for Health Development, Tallinn, Estonia.
Sigrid VorobjovNational Institute for Health Development, Tallinn, Estonia.
Marleen LõhmusSYNLAB Estonia, Tallinn, Estonia.
Martina FuregatoCerner Enviza/Oracle Life Sciences, Paris, France.
Suzanne ReedCerner Enviza/Oracle Life Sciences, Paris, France.
Benjamin BluemelEuropean Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Erika DuffellEuropean Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Kristi RüütelNational Institute for Health Development, Tallinn, Estonia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IntroductionObtaining epidemiological data on chronic hepatitis C virus (HCV) infection is essential to monitor progress towards the hepatitis C elimination targets.AimWe aimed to estimate the prevalence of chronic HCV and the seroprevalence of HCV in the adult general population in Estonia.MethodsThis cross-sectional study, conducted between 12 July and 6 December 2022, included anonymised residual sera collected prospectively from patients 18 years and older visiting a general practitioner in all counties of Estonia. Specimens were considered HCV-seropositive if they tested positive for HCV antibodies by enzyme-linked immunoassay, confirmed by line-immunoblot assay. Chronic HCV infection was determined by positive RT-qPCR.ResultsWe tested a total of 4,217 specimens. The estimated HCV seroprevalence and prevalence of chronic HCV infection were 1.8% (95% CI: 1.4-2.2) and 0.8% (95% CI: 0.5-1.1), respectively, with ca 8,100 persons estimated to have chronic HCV infection in the general adult population of Estonia. No statistically significant differences in the prevalence of chronic HCV infection were observed between sexes, counties or age groups, with the highest prevalence rates observed in men (sex ratio: 1.7), Ida-Virumaa County (1.8%; 95% CI: 0.8-3.6) and the age group 40-49 years (1.7%; 95% CI: 0.9-2.9).ConclusionThis study found an overall low prevalence of chronic HCV infection in Estonia. Continued efforts should be made for the targeted screening, diagnosis and treatment of individuals with chronic HCV infection to achieve hepatitis elimination targets.

Indexed as

HepacivirusHepatitis C AntibodiesHepatitis C, ChronicAdolescentAdultAgedAge DistributionCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayEstoniaFemaleHumansMaleMiddle AgedPrevalenceSeroepidemiologic StudiesHepatitis C Antibodieschronic infectiongeneral populationHepatitis Cprevalenceseroprevalence

Identifiers

PMID39056201
PMCPMC11274846

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.