Evidence map›Paper›PMID 39056200›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2024

Prevalence of chronic hepatitis C infection in the general population: results from a national survey, Romania, 2020 to 2023.

Mira Hleyhel, Odette Popovici, Mihaela Leuștean, Suzanne Reed, Amal Sadou, Martina Furegato, Benjamin Bluemel, Erika Duffell, Otilia Mardh

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Mortality Attributable to Hepatitis B and C in Italy, Romania, and Spain, 2022 Estimates.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. National representative seroprevalence of viral hepatitis B, C, and D seromarkers in Ukraine, 2021.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  6. Article
  7. Hepatitis B and C Screening and Linkage to Care in Migrants From Endemic Countries in Barcelona Through a Community Action.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Article
  8. Article
  9. Article
  10. Towards eliminating hepatitis C as a public health threat: different speeds, different needs.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mira HleyhelCerner Enviza/Oracle Life Sciences, Paris, France.
Odette PopoviciNational Institute of Public Health Romania - National Centre for Surveillance and Control of Communicable Diseases (NCSCCD), Bucharest, Romania.
Mihaela LeușteanNational Institute of Public Health Romania - National Public Health Laboratory, Bucharest, Romania.
Suzanne ReedCerner Enviza/Oracle Life Sciences, Paris, France.
Amal SadouCerner Enviza/Oracle Life Sciences, Paris, France.
Martina FuregatoCerner Enviza/Oracle Life Sciences, Paris, France.
Benjamin BluemelEuropean Centre for Disease Prevention and Control, Stockholm, Sweden.
Erika DuffellEuropean Centre for Disease Prevention and Control, Stockholm, Sweden.
Otilia MardhEuropean Centre for Disease Prevention and Control, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IntroductionA national study from 2006 to 2008 showed a high antibody prevalence of 3.2% against hepatitis C virus (HCV) in Romania, but more recent epidemiological data on hepatitis C prevalence are lacking.AimWe aimed to estimate the current prevalence of HCV antibodies (anti-HCV) and chronic HCV infection in the general adult population in Romania, as a crucial element in monitoring progress towards eliminating hepatitis C.MethodsWe used anonymised leftover sera from a SARS-CoV-2 survey conducted between July and October 2020 (n = 2,100), supplemented with sera collected prospectively between July 2022 and March 2023 (n = 574). These included sera collected from adults visiting laboratories for routine medical check-ups. Sera were tested for anti-HCV and HCV core antigen and classified according to anti-HCV and chronic infection status.ResultsOf the total 2,674 specimens tested, 44 were anti-HCV-positive with a weighted anti-HCV prevalence of 1.4% (95% CI: 1.0-1.9), and 29 were HCV core antigen-positive with a weighted prevalence of chronic infection of 0.9% (95% CI: 0.5-1.2). The prevalence of chronic infection did not differ significantly between men and women. It was higher in persons 60 years and older (2.0%; 95% CI: 1.1-3.0) and in specimens from the North-East region (2.2%; 95% CI: 0.8-3.7).ConclusionAlthough the overall HCV prevalence in Romania is currently low, targeted screening, prevention measures and treatment scale-up are needed especially for the population 60 years and older and in the north-eastern part of the country to achieve the goal of ending the hepatitis C epidemic.

Indexed as

HepacivirusHepatitis C AntibodiesHepatitis C, ChronicAdolescentAdultAgedCOVID-19FemaleHumansMaleMiddle AgedPrevalenceRomaniaSARS-CoV-2Seroepidemiologic StudiesSurveys and QuestionnairesHepatitis C Antibodieschronic infectiongeneral populationHepatitis Cprevalenceseroprevalence

Identifiers

PMID39056200
PMCPMC11274849

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.