Evidence map›Paper›PMID 39056008›Full record

ArticleFrontiers in microbiology2024

Mediation effect of gut microbiota on the relationship between physical activity and carotid plaque.

Wenbin Ouyang, Bei Tang, Yongmei He, Hao Wu, Pingting Yang, Lu Yin, Xiaohui Li, Ying Li, Xin Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wenbin OuyangDepartment of Epidemiology, Hunan Normal University School of Medicine, Changsha, China.
Bei TangDepartment of Epidemiology, Hunan Normal University School of Medicine, Changsha, China.
Yongmei HeDepartment of Health Management, Aerospace Center Hospital, Beijing, China.
Hao WuDepartment of Health Management, The Third Xiangya Hospital, Central South University, Changsha, China.
Pingting YangDepartment of Health Management, The Third Xiangya Hospital, Central South University, Changsha, China.
Lu YinMedical Research & Biometrics Center, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Xiaohui LiDepartment of Pharmacology, Xiangya School of Pharmaceutical Science, Central South University, Changsha, Hunan, China.
Ying Li *Department of Health Management, The Third Xiangya Hospital, Central South University, Changsha, China.
Xin Huang *Department of Epidemiology, Hunan Normal University School of Medicine, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Physical activity has been shown to have an effect on Carotid plaque (CP) which is a predictor of Cardiovascular disease (CVD). Studies have shown that physical activity can alter the composition of gut microbiota, whether its influence on CP was mediated by gut microbiota has yet to be proved. Methods: We conducted a case-control study involving 30 CP patients and 31 controls. Logistic regression was used to analyze the association between CP and physical activity. LefSe was used to explore the association between gut microbiota and physical activity as well as CP, and PhyloMed was used to examine the mediating effect of gut microbiota in the association between physical activity and CP. Results: After adjusting for potential confounders, adequate physical activity showed a significant association with a decreased risk of CP (OR Conclusion: Adequate physical activity was significantly associated with a decreased risk of CP, and this association was mediated by an increase in the abundance of gut microbiota in the order

Indexed as

carotid plaquegut microbiotamediationphylogenetic treephysical activity

Identifiers

PMID39056008
PMCPMC11269180

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.