Evidence map›Paper›PMID 39055826›Full record

ArticleHeliyon2024

Peripheral inflammatory T cell subsets are effective predictive factors in the development of heterotopic ossification after posttraumatic elbow surgery.

Zengfeng Xin, Junhua Chen, Fengbo Huang, Siyu Guo, Yihan Yao, Yang Tang, Hang Li, Qinghua Lv, Ting Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Factors associated with heterotopic ossification following surgical treatment of AO/OTA type C distal humerus fractures: the impact of surgical approach.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zengfeng XinDepartment of Orthopedic Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, University, Hangzhou, China.
Junhua ChenDepartment of Orthopedic Surgery, Second Affiliated Hospital (Jiande Branch), Zhejiang University School of Medicine, Jiande, Hangzhou, China.
Fengbo HuangKey Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, Hangzhou, China.
Siyu GuoKey Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, Hangzhou, China.
Yihan YaoKey Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, Hangzhou, China.
Yang TangKey Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, Hangzhou, China.
Hang LiDepartment of Orthopedic Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, University, Hangzhou, China.
Qinghua LvKey Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, Hangzhou, China.
Ting ZhangKey Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heterotopic ossification refers to the pathological formation of extra-skeletal bone. It is a common complication of trauma or surgery that can cause disability and has no definitive cure. Furthermore, the mechanisms underlying chronic inflammation during ossification remain unclear. Therefore, this study aimed to elucidate the systemic immune microenvironment status of heterotopic ossification and identify biomarkers of therapeutic efficacy and recurrence. A combination of stereoarthrolysis with prophylactic radiotherapy and non-steroidal anti-inflammatory drugs was used to treat patients with heterotopic ossification. Changes were observed in peripheral blood lymphocyte levels after treatment. The number of IFNγ

Indexed as

Heterotopic ossificationImmunityInterferon γOsteogenesisRadiotherapy

Identifiers

PMID39055826
PMCPMC11269831

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.