Evidence map›Paper›PMID 39055712›Full record

ReviewFrontiers in immunology2024

Metabolism and immune memory in invertebrates: are they dissociated?

Texca T Méndez-López, Julio César Carrero, Humberto Lanz-Mendoza, Alejandra Ochoa-Zarzosa, Krishnendu Mukherjee, Jorge Contreras-Garduño

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Animals : an open access journal from MDPI · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. KDM4 Regulates the Glycolysis of Hemocytes in the Immune Priming ofInternational journal of molecular sciences · 2024
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Texca T Méndez-LópezPosgrado en Ciencias Biológicas, Escuela Nacional de Estudios Superiores, Unidad Morelia, Universidad Nacional Autónoma de México, Morelia, Mexico.
Julio César CarreroDepartmento de Immunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México, Mexico.
Humberto Lanz-MendozaInstituto Nacional de Salud Pública, Departamento de Enfermedades Infecciosas, Cuernavaca, Mexico.
Alejandra Ochoa-ZarzosaCentro Multidisciplinario de Estudios en Biotecnología, Universidad Michoacana de San Nicolás de Hidalgo, Morelia, Mexico.
Krishnendu MukherjeeInstitute of Hygiene, University Hospital Müenster, University of Münster, Münster, Germany.
Jorge Contreras-GarduñoInstitute for Evolution and Biodiversity, University of Münster, Münster, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the discovery of specific immune memory in invertebrates, researchers have investigated its immune response to diverse microbial and environmental stimuli. Nevertheless, the extent of the immune system's interaction with metabolism, remains relatively enigmatic. In this mini review, we propose a comprehensive investigation into the intricate interplay between metabolism and specific immune memory. Our hypothesis is that cellular endocycles and epigenetic modifications play pivotal roles in shaping this relationship. Furthermore, we underscore the importance of the crosstalk between metabolism and specific immune memory for understanding the evolutionary costs. By evaluating these costs, we can gain deeper insights into the adaptive strategies employed by invertebrates in response to pathogenic challenges. Lastly, we outline future research directions aimed at unraveling the crosstalk between metabolism and specific immune memory. These avenues of inquiry promise to illuminate fundamental principles governing host-pathogen interactions and evolutionary trade-offs, thus advancing our understanding of invertebrate immunology.

Indexed as

Epigenesis, GeneticHost-Pathogen InteractionsImmunologic MemoryInvertebratesAnimalsBiological EvolutionImmunity, Innateecoimmunologyhost-parasite relationshipimmune primingimmunometabolisminnate immune responsespecific memorytrade-offs

Identifiers

PMID39055712
PMCPMC11269087

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.