Evidence map›Paper›PMID 39055654›Full record

ArticleFrontiers in cell and developmental biology2024

Expression profile and gap-junctional transfer of microRNAs in the bovine cumulus-oocyte complex.

R Six, C Benedetti, Y Fan, X Guan, Y Gansemans, Mohamed Hedia, O Bogado Pascottini, K C Pavani, F Van Nieuwerburgh, D Deforce and 3 more

Abstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Role of miRNAs in Bovine Oocyte Maturation and Reproductive Regulation.International journal of molecular sciences · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

R SixDepartment of Veterinary and Biosciences, Ghent University, Merelbeke, Belgium.
C BenedettiDepartment of Internal Medicine, Reproduction and Population Medicine, Ghent University, Merelbeke, Belgium.
Y FanDepartment of Veterinary and Biosciences, Ghent University, Merelbeke, Belgium.
X GuanDepartment of Veterinary and Biosciences, Ghent University, Merelbeke, Belgium.
Y GansemansLaboratory of Pharmaceutical Biotechnology, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.
Mohamed HediaDepartment of Internal Medicine, Reproduction and Population Medicine, Ghent University, Merelbeke, Belgium.
O Bogado PascottiniDepartment of Internal Medicine, Reproduction and Population Medicine, Ghent University, Merelbeke, Belgium.
K C PavaniDepartment of Internal Medicine, Reproduction and Population Medicine, Ghent University, Merelbeke, Belgium.
F Van NieuwerburghLaboratory of Pharmaceutical Biotechnology, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.
D DeforceLaboratory of Pharmaceutical Biotechnology, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.
K SmitsDepartment of Internal Medicine, Reproduction and Population Medicine, Ghent University, Merelbeke, Belgium.
A Van SoomDepartment of Internal Medicine, Reproduction and Population Medicine, Ghent University, Merelbeke, Belgium.
L PeelmanDepartment of Veterinary and Biosciences, Ghent University, Merelbeke, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNA) are important regulators of oocyte maturation, playing a key role in modulating gene expression both in a temporal- and spatial-specific manner. These small non-coding RNAs are involved in important processes during oocyte maturation, acting as messengers between the oocyte and its surrounding cumulus cells. Despite its significance, the bidirectional communication mechanism is still unknown. To test miRNA communication between oocyte and surrounding cumulus cells through the gap junctions the gap junctions were either blocked with carbenoxolone or not. MiRNA sequencing of oocytes at 1, 6, and 22 h of

Indexed as

bovine oocytecumulus cellsgap junctionintercellular communicationmaturationmiRNA

Identifiers

PMID39055654
PMCPMC11269113

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.