Evidence map›Paper›PMID 39055628›Full record

ArticleInternational journal of transgender health2024

The efficacy of and user satisfaction with different antiandrogens in Chinese transgender women.

Wenhui Yang, Tianpei Hong, Xu Chang, Meng Han, Hongwei Gao, Bailin Pan, Zhenmin Zhao, Ye Liu

Abstract read
In one paragraph

Article in International journal of transgender health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenhui YangDepartment of Plastic Surgery, Peking University Third Hospital, Beijing, China.
Tianpei HongDepartment of Endocrinology and Metabolism, Peking University Third Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-5744-5129
Xu ChangDepartment of Plastic Surgery, Peking University Third Hospital, Beijing, China.
Meng HanDepartment of Medical Psychology, The School of Health Humanities, Peking University, Beijing, China.
Hongwei GaoDepartment of Endocrinology and Metabolism, Peking University Third Hospital, Beijing, China.
Bailin PanDepartment of Plastic Surgery, Peking University Third Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-2563-8997
Zhenmin ZhaoDepartment of Plastic Surgery, Peking University Third Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-7177-2169
Ye LiuDepartment of Endocrinology and Metabolism, Peking University Third Hospital, Beijing, China.ORCID https://orcid.org/0000-0003-1922-0196

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Cyproterone acetate (CPA) and spironolactone (SPL) are different antiandrogens in gender-affirming hormone therapy (GAHT) for transgender women. Few studies have evaluated their efficacy and user satisfaction, especially among East Asians. This study aimed to evaluate these aspects in Chinese transgender women. Methods: Data were collected retrospectively from transgender women visiting the Peking University Third Hospital from 2012 to 2021. From 639 people identified as transgender women, 151 of them (80 using CPA and 71 using SPL, 16 to 40-year-old) under stable GAHT ≥6 months were enrolled. Total testosterone levels and visual analogue scale (VAS)-based satisfaction scores were evaluated. Results: No difference was observed in age between the CPA and SPL groups (median [IQR], 22 [20-24] years and 23 [20-26] years, respectively). The duration of GAHT was longer in CPA group than in SPL group (18 [10-32] months vs. 12 [8-21] months, Conclusion: In Chinese transgender women, CPA was more effective than SPL in lowering testosterone levels. Additionally, VAS scores indicated greater satisfaction with erection decreased and figure feminization using CPA compared to SPL.

Indexed as

Antiandrogencyproterone acetatespironolactonetransgender women

Identifiers

PMID39055628
PMCPMC11268237

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.