Evidence map›Paper›PMID 39055453›Full record

ArticleCureus2024

Numerous Asymptomatic Brain Tuberculomas Complicated by Fatal Tuberculous Meningitis.

Irakli Alavidze, Mariam Shubitidze, Gvantsa Khodeli, Shorena Dvali, Aleksandre Tskitishvili

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Irakli AlavidzeAieti Medical School, David Tvildiani Medical University, Tbilisi, GEO.
Mariam ShubitidzeAieti Medical School, David Tvildiani Medical University, Tbilisi, GEO.
Gvantsa KhodeliSchool of Medicine, Ilia State University, Tbilisi, GEO.
Shorena DvaliHIV/AIDS Department, Infectious Diseases, AIDS and Clinical Immunology Research Center, Tbilisi, GEO.
Aleksandre TskitishviliAieti Medical School, David Tvildiani Medical University, Tbilisi, GEO.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) is still one of the most challenging infectious diseases worldwide. Coinfection with HIV increases the likelihood of extrapulmonary involvement, including the tuberculosis of the central nervous system (CNS-TB). CNS-TB often presents as tuberculomas or tuberculous meningitis. Although tuberculomas can be single or multiple, asymptomatic carriage of numerous tuberculomas is seldom reported. We present a case of a 55-year-old man who carried at least 34 tuberculomas of different sizes asymptomatically before developing and succumbing to tuberculous meningitis. Furthermore, we highlight several possible public health challenges that might have complicated his clinical course, suggesting that future studies also focus on these variables alongside more traditional clinical issues.

Indexed as

central nervous system tuberculosisgeorgiaglobal health policyhiv aidsimmunosuppresionintracranial tuberculomamedication noncompliancepublic healthtuberculous meningitis (tbm)

Identifiers

PMID39055453
PMCPMC11270632

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.