Evidence map›Paper›PMID 39055199›Full record

ArticleFood science & nutrition2024

Exploring the cholesterol-lowering effects of cereal bran cell wall-enriched diets.

Tabussam Tufail, Farhan Saeed, Tanazzam Tufail, Huma Bader Ul Ain, Muzzamal Hussain, Sana Noreen, Mohd Asif Shah

Abstract read
In one paragraph

Article in Food science & nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tabussam TufailSchool of Food and Biological Engineering, Jiangsu University Zhenjiang China.ORCID https://orcid.org/0000-0002-7632-5261
Farhan SaeedDepartment of Food Sciences Government College University Faisalabad Faisalabad Pakistan.ORCID https://orcid.org/0000-0001-5340-4015
Tanazzam TufailFaisalabad Medical University Faisalabad Pakistan.
Huma Bader Ul AinUniversity Institute of Diet & Nutritional Sciences The University of Lahore Lahore Pakistan.
Muzzamal HussainDepartment of Food Sciences Government College University Faisalabad Faisalabad Pakistan.
Sana NoreenUniversity Institute of Diet & Nutritional Sciences The University of Lahore Lahore Pakistan.
Mohd Asif ShahDepartment of Economics Kabridahar University Kabridahar Somali Ethiopia.ORCID https://orcid.org/0000-0002-0351-9559

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell wall polysaccharides (dietary fiber) in cereal grains contribute to health benefits. The novelty of the current study was an effort to explore the in vivo therapeutic potential of different cereal bran cell walls against hypercholesterolemia. For this purpose, the cell walls were isolated from different cereal brans (wheat, maize, oats, and barley), and the intake of these cereal bran cell walls was evaluated for their anti-lipidemic activity in normal and hypercholesterolemic rats. The serum taken from the rats was tested for cholesterol, lipid, and triglyceride profiles before and after treatment. The outcomes of the current study have shown that the cereal cell wall has a significant hypercholesterolemia effect. The biochemical parameters of the control animals were within the normal clinical ranges, indicating that the experimental diets were safe. Among cereal bran cell walls, barley bran significantly decreased cholesterol (56.35 ± 1.35 mg/dL), low-density lipoprotein (56.35 ± 1.05 mg/dL), triglycerides (105.29 ± 1.95 mg/dL), and increased high-density lipoprotein level (48.35 ± 1.35 mg/dL). These findings provide conclusive evidence that the cereal cell wall is beneficial in the treatment of hypercholesterolemia and may potentially provide protection against other acute, recurring, or chronic illnesses.

Indexed as

cell wallcereal grainhypercholesterolemiapolysaccharides

Identifiers

PMID39055199
PMCPMC11266912

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.