Evidence map›Paper›PMID 39055164›Full record

ReviewDrug design, development and therapy2024

Nanoparticle-Based Drug Delivery Systems for Inflammatory Bowel Disease Treatment.

Jian Gao, Jiannan Li, Zengyou Luo, Hongyong Wang, Zhiming Ma

Abstract readReview
In one paragraph

Review in Drug design, development and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
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  7. Recent advances in the positive role ofFrontiers in immunology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jian GaoDepartment of Gastrointestinal Nutrition and Hernia Surgery, The Second Hospital of Jilin University, Changchun, People's Republic of China.
Jiannan LiDepartment of Colorectal and Anal Surgery, The Second Hospital of Jilin University, Changchun, People's Republic of China.
Zengyou LuoDepartment of Gastrointestinal Nutrition and Hernia Surgery, The Second Hospital of Jilin University, Changchun, People's Republic of China.
Hongyong WangDepartment of Radiotherapy, The Second Hospital of Jilin University, Changchun, People's Republic of China.
Zhiming MaDepartment of Gastrointestinal Nutrition and Hernia Surgery, The Second Hospital of Jilin University, Changchun, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a chronic, non-specific inflammatory condition characterized by recurring inflammation of the intestinal mucosa. However, the existing IBD treatments are ineffective and have serious side effects. The etiology of IBD is multifactorial and encompasses immune, genetic, environmental, dietary, and microbial factors. The nanoparticles (NPs) developed based on specific targeting methodologies exhibit great potential as nanotechnology advances. Nanoparticles are defined as particles between 1 and 100 nm in size. Depending on their size and surface functionality, NPs exhibit different properties. A variety of nanoparticle types have been employed as drug carriers for the treatment of inflammatory bowel disease (IBD), with encouraging outcomes observed in experimental models. They increase the bioavailability of drugs and enable targeted drug delivery, promoting localized treatment and thus enhancing efficacy. Nevertheless, numerous challenges persist in the translation from nanomedicine to clinical application, including enhanced formulations and preparation techniques, enhanced drug safety profiles, and so forth. In the future, it will be necessary for scientists and clinicians to collaborate in order to study disease mechanisms, develop new drug delivery strategies, and screen new nanomedicines. Nevertheless, numerous challenges persist in the translation from nanomedicine to clinical application, including enhanced formulations and preparation techniques, enhanced drug safety profiles, and so forth. In the future, it will be necessary for scientists and clinicians to collaborate in order to study disease mechanisms, develop new drug delivery strategies, and screen new nanomedicines.

Indexed as

Drug Delivery SystemsInflammatory Bowel DiseasesNanoparticlesAnimalsDrug CarriersHumansNanomedicineNanoparticle Drug Delivery SystemDrug CarriersNanoparticle Drug Delivery Systemactive targetingdrug delivery systeminflammatory bowel diseasesnanoparticlespassive targetingtargeted delivery

Identifiers

PMID39055164
PMCPMC11269238

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.